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The Pulse of the Pharmaceutical Industry

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Physician burnout takes a toll on U.S. patients

Nearly two-thirds of U.S. doctors feel burned out, depressed, or both – and those feelings affect how they relate to patients, according to a survey conducted by Medscape.

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Kymriah wins speedy reviews in U.S., Europe

Novartis was granted fast-track reviews of its cell therapy Kymriah for blood cancers in the United States and Europe.

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Imprimis receives FDA warning

The U.S. FDA issued a warning letter to Imprimis Pharmaceuticals Inc. accusing it of making false or misleading claims that its compounded eye medications had the agency’s approval.

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FDA expects IV fluid shortage to improve in coming weeks, months

The U.S. FDA expects a shortage of intravenous saline fluids for hospitals due to damage to key manufacturing facilities in Puerto Rico to improve over the coming weeks and months.

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U.S. healthcare uninsured rises most in near decade: Gallup

The number of Americans without healthcare insurance rose by 3.2 million people between 2016 and 2017 – or 1.3 percentage points to 12.2 percent – according to a Gallup poll, the biggest jump in the uninsured rate in nearly a decade.

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FDA to speed review of military medical products

The U.S. FDA and Department of Defense launched a program to speed up the development of drugs that could be used by military personnel.

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Eiger to abandon blood pressure drug

Eiger BioPharmaceuticals Inc. will stop development of a drug to treat pulmonary arterial hypertension after it failed in a mid-stage study.

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Keytruda extends lung cancer survival in study

A cocktail of Merck & Co. Inc.’s blockbuster drug Keytruda and two chemo medicines helped lung cancer patients live longer and stopped the disease from advancing.

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German watchdog calls for direct comparison of cancer immunotherapies

Germany’s drug assessment body criticized a lack of data directly comparing drugs in a promising new class of cancer immunotherapy, saying physicians could be overwhelmed or misled by the available information.

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Google venture arm backs UK universal flu vaccine company

A private British company is developing a vaccine that would be the first in the world to fight all types of flu.

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FDA approves expanded use of AstraZeneca drug

The U.S. Food and Drug Administration approved expanded use of AstraZeneca Plc’s cancer drug Lynparza.

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Drugmakers see a pricing blueprint in an $850,000 gene therapy

Global drugmakers are looking to a tiny biotech’s $850,000 therapy for a rare type of blindness as a model for getting paid for highly expensive – and effective – new medicines.

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Roche MS medicine Ocrevus wins EU approval

The European Union approved Roche’s multiple sclerosis medicine Ocrevus, one of the Swiss company’s key new drugs.

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U.S. subpoenas Endo for info on opioid painkillers

Endo International received a grand jury subpoena from federal prosecutors in Miami seeking documents related to drugs it produces that contain oxymorphone.

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Smaller social network tied to bigger diabetes risk

Socially isolated people may be more likely to develop diabetes than adults with closer ties to family and friends, a recent study suggests.

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Bayer, J&J win reversal of Xarelto lawsuit verdict

A Pennsylvania state court judge overturned a $27.8 million jury award to an Indiana couple who accused Bayer and J&J of failing to warn of internal bleeding risks.

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Human antibodies made in cows could be developed to treat MERS

Human antibodies made in genetically engineered cows have proved safe in an early-stage clinical trial.

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U.S. pharma executives expect deals to pick up

The Trump administration’s tax overhaul should accelerate major acquisitions by drugmakers in 2018, say senior execs from some of the largest manufacturers.

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Drug charity sues U.S. over restrictions on donor communications

A U.S. charity offering assistance to patients on out-of-pocket drug costs sued the federal government over restrictions on its ability to communicate with drugmakers who donate to it.

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Centene: 1.4+ million sign up for 2018 Obamacare

U.S. health insurer Centene Corp. said more than 1.4 million people had paid for its insurance plans via the federal Obamacare marketplace as of Jan. 7, 2018.

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