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AbbVie cancer drug fails two late-stage trials

AbbVie Inc. said its experimental cancer drug, veliparib, failed to meet the main goals of two late-stage studies.

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Gates backs push to wipe out tropical diseases

The Bill and Melinda Gates Foundation, Western countries and drug companies pledged fresh support to wipe out diseases in tropical areas.

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OncoMed Lung Cancer Med Fails Phase II

Shares of OncoMed Pharmaceuticals were down after the company announced its mid-stage combination lung cancer treatment failed to meet endpoints.

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Hemophilia drug: positive results with children

Roche’s emicizumab drug for treating hemophilia A showed positive interim results in a phase III study with children with inhibitors to clotting protein factor VIII.

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OncoMed sinks as cancer drug fails

OncoMed Pharmaceuticals is discontinuing a trial testing its experimental drug demcizumab as an initial therapy for advanced pancreatic cancer.

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Roche’s Alecensa notches trial win against Pfizer’s Xalkori

Roche’s Alecensa kept people with a specific lung cancer alive longer without their disease progressing than Xalkori as it seeks to move in on Pfizer’s share of early treatment of the disease.

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Takeda study brings dengue vaccine step closer

Takeda Pharmaceutical completed enrollment for a 20,000-subject dengue vaccine trial, the largest clinical study in the company’s history.

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Common antibiotic could prevent or treat PTSD

A common antibiotic called doxycycline can disrupt the formation of negative thoughts and fears in the brain and may prove useful in treating or preventing post traumatic stress disorder (PTSD), according to research by British and Swiss scientists.

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Immunotherapy combo extends melanoma survival

Patients with advanced melanoma who received Bristol-Myers Squibb’s immunotherapies Opdivo and Yervoy had improved overall survival versus those on Yervoy alone.

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Vertex CF combo succeeds in late-stage trials

Vertex Pharmaceuticals Inc. said its Kalydeco cystic fibrosis treatment given with an experimental drug demonstrated significant improvements in lung function in a pair of late-stage trials the company plans to use to seek approval of the combination therapy.

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Foamix’s acne drug misses main goal in key study

Foamix Pharmaceuticals Ltd. said its experimental acne treatment failed to meet one of two main goals in a late-stage study, pushing its shares down about 42 percent.

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Ultragenyx Seizure Drug Flunks Phase II Test

Shares of Ultragenyx Pharmaceuticals were down after the company announced its Phase II drug UX007 to treat seizures failed to meet trial goals.

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GSK and Regeneron to mine gene data

GlaxoSmithKline and Regeneron Pharmaceuticals are embarking on a joint project with UK Biobank to hunt for new clues linking genes and disease.

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Novartis heart drug serelaxin fails study

Novartis’ heart failure drug serelaxin flopped in a late-stage trial by not cutting cardiovascular death or slowing disease progression, marking the likely demise of a drug hopeful the Swiss firm had promoted as a potential blockbuster.

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Breast cancer drug combo succeeds key study

Eli Lilly and Co.’s combination of its experimental breast cancer drug abemaciclib and another widely used treatment slowed disease progression.

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Nektar’s opioid painkiller succeeds in key study

Nektar Therapeutics said its experimental opioid succeeded in a key late-stage study.

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Catalyst’s neuromuscular drug succeeds in study

Catalyst Pharmaceuticals Inc.’s experimental drug to treat patients with a severe form of myasthenia gravis, a rare neuromuscular disease, met the main goals of a study.

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FDA Grants Orphan Drug Designation to CSRA’s DynPort Vaccine Company for Plague Vaccine

DynPort’s clinical stage recombinant Yersinia pestis rF1V plague vaccine to benefit from FDA Orphan Drug Designation FALLS CHURCH, Va., March 8, 2017 /PRNewswire/ — CSRA Inc. (NYSE: CSRA) today announced that a plague vaccine being developed by its subsidiary, DynPort Vaccine Company LLC (DVC), was granted Orphan Drug Designation from the U.S. Food and Drug Administration […]

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Precision Medicine: What Is It And Why Now?

Nearly two decades ago, the promise of precision medicine began making its mark on the pages of medical journals – along with speculation that “therapy with the right drug at the right dose in the right patient” – would define the future of medical treatment.

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Latest Dupixent eczema drug tests positive

Sanofi and Regeneron said results from a one-year test of Dupixent aimed at adults with eczema or moderate-to-severe atopic dermatitis had been positive.

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