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Amgen Forges Pre-clinical R&D Pact With Advaxis

Amgen Inc. struck a research and development deal for the development of Advaxis Inc.’s pre-clinical immunotherapy treatment, ADXS-NEO.

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Struggling Telesta Cuts Another 30% of Workforce

Telesta Therapeutics will terminate its bladder cancer drug MCNA project, shutter its Montreal-based manufacturing facility and terminate another 30 percent of its workforce.

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Takeda to Now Focus on Three Therapeutic Areas

Takeda will refocus R&D on three targeted therapeutic areas – oncology, gastroenterology and CNS. Vaccines will also continue to play an important role.

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AstraZeneca Kills Six Pipeline Programs

Along with its dismal half-year financial reports, UK-based AstraZeneca announced it was halting six pipeline programs.

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Alzheimer’s drug fails in study; some benefit seen

TauRx Pharmaceuticals’ experimental Alzheimer’s drug LMTX failed to improve cognitive and functional skills in patients with mild to moderate Alzheimer’s disease.

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IBM steps up efforts in fight against Zika

International Business Machines Corp. said it would provide its technology and resources to help track the spread of the Zika virus.

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Phase III Trials Halted for Lung Cancer Drug Gilotrif

Boehringer Ingelheim was forced to halt two Phase III trials for lung cancer drug Gilotrif following the advice of a data monitoring committee, Pharma Times reported.

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FDA Lifts Clinical Hold On CGF166

GenVec was notified by its collaborator Novartis that FDA has lifted the clinical hold on the Phase 1/2 clinical trial of CGF166 in patients with severe to profound hearing loss.

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Malaria drug may help in cancer fight

An off-patent malaria drug could help to destroy cancer cells by making them more susceptible to radiotherapy, according to early research.

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Lymphoma Drug Flunks Phase III Test

Gazyva combined with chemotherapy failed to meet its primary endpoints in a Phase III trial for patients with previously untreated diffuse large B-cell lymphoma.

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AstraZeneca’s lung cancer drug meets main goal in late-stage trial

AstraZeneca Plc said its experimental lung cancer drug Tagrisso met its main goal in a late-stage study.

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Ziopharm Reports Clinical Trial Death

Boston’s Ziopharm Oncology released information that a patient receiving gene therapy into a brain tumor died from an intracranial hemorrhage.

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Scientists: Zika outbreak to end in two to three years

The Zika outbreak rampaging through Latin America will likely burn itself out in the next two to three years, based on the fact that people develop immunity to the virus after an initial infection, British scientists said.

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Study casts doubt on ‘obesity paradox’

Being overweight or obese is linked to a higher risk of dying prematurely than being normal weight and the risk rises sharply as the extra pounds pile on, scientists said.

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PPD drug succeeds in mid-stage study

Sage Therapeutics Inc. said its lead drug alleviated symptoms of severe postpartum depression, meeting the main goal of a small mid-stage study.

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Merck: Outsmarting Superbugs

Merck is globally committed to an antimicrobial stewardship encompassing surveillance, R&D, and health policy.

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Diabetes study: Many common genes at play

A study examining genes of more than 120,000 people from Europe, Asia, Africa and the Americas has offered the clearest picture yet of those that drive type 2 diabetes.

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France’s Valneva says has generated possible Zika vaccine

French biotech firm Valneva said it has produced a possible vaccine against the mosquito-borne Zika virus.

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Blockbuster hopes grow for Ablynx drug

Ablynx’s hopes for a potential multibillion-dollar drug were boosted by strong clinical trial results in rheumatoid arthritis.

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Sanofi partners U.S. Army to speed up Zika vaccine

French drugmaker Sanofi struck an R&D deal with the U.S. Army to speed up the development of a vaccine against the mosquito-borne Zika virus.

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