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Orexigen says obesity drug safety trial terminated

Orexigen Therapeutics Inc and its partner Takeda Pharmaceutical Co said they were terminating a trial assessing the cardiovascular safety of obesity drug, Contrave. Orexigen Therapeutics shares were down 12.5 percent in after market trading after falling 13.6 percent in regular trading on the Nasdaq on Tuesday. The study was not being terminated due to the […]

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AstraZeneca digs into precision medicine with lung, heart deals

A sign is seen at an AstraZeneca site in Macclesfield, central England May 19, 2014. Reuters/Phil Noble AstraZeneca is diving deeper into personalized healthcare with two projects that move the concept beyond cancer into respiratory disorders and heart disease. Personalized or precision medicine, which tailors treatment to a patient’s genetic profile, is an increasing focus […]

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Orexigen says obesity drug safety trial terminated

A trial assessing the cardiovascular safety of obesity drug Contrave, made by Orexigen Therapeutics Inc and Takeda Pharmaceutical Co Ltd, was terminated on Tuesday due to unauthorized release of study data. A statement from Cleveland Clinic, which was conducting the trial, said the study was being halted as unauthorized release of trial data by Orexigen […]

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New Malaria Test Could Lead to Global Eradication of the Disease

WASHINGTON, May 11, 2015 /PRNewswire-USNewswire/ — One of the biggest difficulties faced by worldwide programs aimed at eliminating malaria is that the tests they use are not sensitive enough to detect all people who have the disease and need treatment. A study appearing online today in Clinical Chemistry, the journal of AACC, shows that a new […]

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Vivione Biosciences Inc. Announces a Research Collaboration With Northwestern University Feinberg School of Medicine

DALLAS, TX–(Marketwired – May 11, 2015) – Vivione Biosciences Inc. (“Vivione” or the “Company”) (TSX VENTURE: VBI), is pleased to announce a research collaboration with Northwestern University Feinberg School of Medicine located in Chicago, Illinois. The collaboration will focus on the rapid detection of low levels of bacteria in clinical blood samples, as well the […]

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Childhood cancer treatment and age influence obesity risk for childhood cancer survivors

MEMPHIS, Tenn., May 11, 2015 /PRNewswire-USNewswire/ —  Childhood cancer survivors – especially those whose treatment included brain irradiation or chemotherapy with glucocorticoids – are 14 percent more likely to be obese than their healthy peers. The St. Jude Children’s Research Hospital study appears today in the journal Cancer. Of the 1,996 childhood cancer survivors in […]

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First cancer-promoting oncogenes discovered in rare brain tumor of children and adults

MEMPHIS, Tenn., May 11, 2015 /PRNewswire-USNewswire/ — Researchers have identified three genes that play a pivotal role in the brain tumor choroid plexus carcinoma (CPC), a discovery that lays the groundwork for more effective treatment of this rare, often fatal cancer. St. Jude Children’s Research Hospital scientists led the study, which appears today in the […]

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Lilly and BioNTech Announce Research Collaboration on Novel Cancer Immunotherapies

INDIANAPOLIS and MAINZ, Germany, May 11, 2015 /PRNewswire/ — Eli Lilly and Company (NYSE: LLY) and BioNTech AG today announced they have entered into a research collaboration to discover novel cancer immunotherapies. The companies will seek to use the power of the body’s own immune system to attack cancer cells and create possible new treatment options […]

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Drug-resistant ‘superbug’ strain of typhoid spreads worldwide

An antibiotic-resistant “superbug” strain of typhoid fever has spread globally, driven by a single family of the bacteria, called H58, according to the findings of a large international study. The research, involving some 74 scientists in almost two dozen countries, is one of the most comprehensive sets of genetic data on a human infectious agent […]

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As Ebola disappears, no useful data seen from vaccine trials: WHO

People hold the Liberian flag with a Christian cross on it during an official celebration of the country being declared Ebola-free, in Monrovia, Liberia, May 11, 2015. Reuters/James Giahyue With Ebola nearly stamped out in West Africa, vaccine trials will probably fail to provide enough useful data on how well they protect people against the […]

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Endo Pharmaceuticals Shells Out $130 Million for Nearly 70 Pipeline Programs From Aspen Pharmacare Holdings

DUBLIN — Endo International (ENDP) has continued its trend of expanding its portfolio through acquisitions, announcing a $130 million deal to acquire a large portfolio of anti-pain anti-infectives, cardiovascular and other therapeutics areas from Aspen Pharmacare Holdings, the company said this morning. The deal includes products that are currently on the market, as well as […]

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U.S. FDA Issues Complete Response Letter to sNDA Seeking to Expand the Label for INVEGA SUSTENNA®

TITUSVILLE, N.J., May 11, 2015 /PRNewswire/ — Janssen Pharmaceuticals, Inc. announced today that the U.S. Food and Drug Administration (FDA) issued a Complete Response letter regarding the supplemental new drug application (sNDA) for once-monthly long-acting antipsychotic INVEGA SUSTENNA® (paliperidone palmitate). The sNDA seeks to expand the product’s label to include data showing that treatment with INVEGA SUSTENNA® […]

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New Study Explains How Too Much Artificial Light Might Be Making You Fat

Scientists in the Netherlands were able to make mice fat just by exposing them to 24 hours a day of artificial light. The fat mice didn’t eat more or exercise less than their thin counterparts – the main difference the researchers observed was in the activity of a substance called brown fat, which, counterintuitively, functions […]

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How Chewing Gum Can Stop Unwanted Songs From Playing In Your Head

An “earworm” is a song that won’t stop playing in your head. It’s annoying for sure, and if it goes on too long the effect can be a bit maddening. A new study shows that it’s possible to chew away the earworms with a couple sticks of your favorite gum. How this works is intriguing. […]

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UNC-Chapel Hill and GSK announce novel partnership to accelerate search for HIV cure

CHAPEL HILL, N.C., May 10, 2015 /PRNewswire-USNewswire/ — The University of North Carolina at Chapel Hill, a leading global public research university with significant expertise in HIV basic and clinical research, and GSK, a global, research-based pharmaceutical and healthcare company with a legacy of success in developing treatments for HIV, today announced the creation of the […]

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Hunt for AIDS cure accelerates as GSK and U.S. experts link up

Britain’s GlaxoSmithKline, which decided last week to retain rather than float off its HIV drugs business, is to collaborate with U.S. scientists in developing a cure for AIDS. Until recently, many researchers were reluctant to even discuss the possibility of curing the disease caused by HIV, which infects 35 million people worldwide, since the obstacles […]

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Osteoporosis linked to higher risk of sudden deafness

(Reuters Health) – People with osteoporosis may be almost twice as likely to develop sudden hearing loss, compared to people without the bone disease, according to researchers in Taiwan. The cause of this sudden deafness is unknown, but the rapid loss of hearing typically affects one ear, and it’s estimated to strike about one in […]

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Amarin Reports First Quarter 2015 Financial Resultsand Provides Update on Operations

REDUCE-IT Cardiovascular Outcomes Study Continuing on Schedule; Product Revenue Increased 42% Over Same Period Last Year; Conference Call Set for 8:00 a.m. EST Today BEDMINSTER, NJ, and DUBLIN, IRELAND–(Marketwired – May 08, 2015) – Amarin Corporation plc (NASDAQ: AMRN), a biopharmaceutical company focused on the commercialization and development of therapeutics to improve cardiovascular health, today announced financial […]

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Diabetics who quit smoking may have trouble controlling blood sugar

(Reuters Health) – Although smoking increases the risk of diabetes and quitting has numerous health benefits, diabetics who quit may have temporary difficulty controlling their symptoms, a British study finds. Researchers reviewed medical records for 10,692 adult smokers with diabetes in the UK and found that smoking cessation led to an uptick in blood sugar […]

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Measles Vaccine Reduces Death From Other Infections Too – By Preventing ‘Immune Amnesia’

If there were ever any doubt that measles is a dangerous disease, a study published in the journal Science yesterday blows that misconception away by finally explaining how large-scale measles vaccination caused such a plummet in childhood deaths – even from infections that seemed unrelated to measles. Aside from the risk of death and disability that […]

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