Pharmalot... Pharmalittle... Good Morning

Hello, everyone, and nice to see you again. We have just returned from a much-needed week's vacation and, as you know, we ran a heavy dose of op-ed columns, a feature we occasionally employ, instead of the usual mix of newsie items and analysis. In any event, we hope these were enjoyable and we will, of course, continue to run op-eds in the future. Meanwhile, thanks to our colleagues Chris Truelove, Josh Slatko and Mia Burns for the assistance. Now, of course, it is back to business, although our late arrival means we are playing catch up today. We trust you understand, given that the world did not stop spinning in our absence. So, yes, we are brewing a cup of stimulation as we sift through large mountains of e-mails and assorted reading matter. Meanwhile, here are some tidbits. Hope your day goes well...

Peregrine Blames Contractors For Faulty Study Data (Regulatory Focus)

Feds Probe Questcor Promotional Practices (Bloomberg News)

Study Divides Breast Cancer Into Four Different Types (New York Times)

Dueling Tests Pressure Roche Bet On Herceptin (Bloomberg News)

Illinois Cannot Force Pharmacies To Give Morning After Pill (Reuters)

KV Protests Hologic Bid To Acquire Makena (Dow Jones)

EMA Issues Recommendations For Pfizer, Bristol And Novartis (PharmaTimes)

Novartis Drug Reduces Heart Failure Deaths In Study (Reuters)

Judge Orders Release Of J&J's Ethicon Safety Data (Legal Examiner)

Clinical Trials Should Include More Elderly (Outsourcing Pharma)

PhRMA Wants To Boost US Government Spending On Drugs (Bloomberg News)

EDITOR'S NOTE: Please check this post for updates

sunrise pic thx to benimoto on flickr

41 Comments

Sep 24, 2012 - 9:03am
My friend is a vascular surgeon. Next time a pharmacist comes into his ER with a ruptured aortic aneurysm in hypovolemuc shock I'll tell him not to operate because his sonscientious objection to taking care of pharmacists.
Sep 24, 2012 - 9:11am
Pregnancy is not lethal or harmful, usually. But you may give birth to idiotz.
Sep 24, 2012 - 9:16am
OII when your friend is required to perform abortions then we can require pharmacies to stock and dispense the morning after pill. Until then both can be handled the same way - by referring the patient to someone who provides these services which is perfectly legal and ethical.
Sep 24, 2012 - 11:01am
Mc, my dad the surgeon used to tell me about women who tried to abort themselves before abortion became legal. Many of these women died from infection and if lucky to survive became infertile because of scarred fallopian tubes or having had to undergo an emergency hysterectomy. Maybe if these bead rattlers saw a few of these female organs in such situations they might reconsider their position. Hard to do when you're whole job exist behind a counter and you never have to see the consequences of your inaction.
Sep 24, 2012 - 1:29pm
Last I checked abortions are legal and available. Physicians have a choice whether to perform them just as a pharmacist can decide what to stock. Personally I don't care who gets an abortion or takes Plan B. I do have an issue with the government mandating that those services be provided. If that is to be the case then hand them out at the flipping post office.
In regards to the "Study Divides Breast Cancer Into Four Different Types." Competing financial interests: Charles M. Perou and Matthew J. Ellis are inventors on patent filing for PAM50 (a RT-qPCR assay Breast Cancer Intrinsic Classifier) and have equity interest in Bioclassifier LLC (breast cancer classification technology licensed to NanoString, which intends to develop a diagnostic test for clinical use).
Sep 24, 2012 - 1:51pm
I guess Canada will eventually be on the list of countries that are an existential threat to USA...cut and pasted from the internet after a search for "available over the counter":

Plan B is available over the counter in the provinces and territories listed below. plan B can be found in one of the following sections: Birth Control, Contraceptives, Feminine Hygiene or Family Planning. If you can’t find it, ask a pharmacist or a pharmacist’s assistant.

Alberta British Columbia Manitoba New Brunswick Newfoundland and Labrador Nova Scotia Nunavut Northwest Territories Ontario Prince Edward Island Yukon

Sep 24, 2012 - 2:05pm
dzieczko, Plan B is available over the counter in the good old USA - AT PHARMACIES THAT CHOOSE TO STOCK IT. Which is as it should be. Like I said above, if the goverment wants to mandate access to Plan B, let federal employees manage it. Mail carriers can keep them in their pouches along with dog biscuits and mace.
Sep 24, 2012 - 2:29pm
@MC RPh - when the "government" decreed that the selling of booze was prohibited, it still got sold underground, so to speak.

No one cares if you don't sell it at your pharmacy....

Sep 24, 2012 - 2:33pm
Based on his posts above strangely enough OII cares.
Sep 24, 2012 - 3:05pm
I actually have a problem with doctors who refuse to perform abortions, although I am agnostic. A doctor is trained to heal and serve, and abortion is only the most public of any number of biases a doctor could use in deciding not to treat a patient. That's what separates doctors from other health care professionals. They don't get to choose who walks in the door.

To me the doctor who refuses to perfom a life changing procedure is just as bad as the old "hyster heisters" from dad's day where many African American women from the ghetto underwent hysterectomy in tandem with removal of a unilateral ovarian cyst because the the white OB-GYN felt it his obligation to keep the minority population under control. Stunning, but absolutely true.

Yes, I do care-most of the time.

Sep 24, 2012 - 3:16pm
I believe that doctors have the ability to choose what elective services they offer just the same as a pharmacist may choose what products to stock in their pharmacy. A simple referral to another practioner that does provide these services does not prevent anyone from getting them. With the direction we are heading the freedom to make these choices will soon be gone. The great government God will mandate all.
Sep 24, 2012 - 4:50pm
@MC RPh - Blankfein of Goldman Sachs stated that he's doing "god's work", OII quotes the surgeon in the movie saying "I AM God", and you are "god" in your own pharmacy.

I would have to admit that given those choices for "godship", I'll choose being an atheist.

If you only want to perform certain procedures - then be a "specialist", right?

50% of practicing physicians don't like their "job". Talk about a profession in serious need of "education reform".

I won't unearth the rock that opens up the study of the gene pool of men who know that if left to a woman's choice, it's the end of their passing on of their genetic material. It was real clear in brutal days past and still is, even when 31 states grant the rapist child visitation rights, that another gene pool has no problem with Plan B and/or abortion to make sure their women aren't a means to propagation of the "other".

How about a public service announcement compromise? National registry for the places the migrating homeless/jobless masses of women should not go to since their misery will only increase based on the god's that rule the resources.

Sep 24, 2012 - 7:10pm
It is an unwritten rule of medicine that specialists don't refer to other specialists in the same field if they can technically do the themselves. That's what gp's do. You tell me that that a woman who is up against the legal clock comes to you got an abortion that you are trained to do and you refer her maybe hundreds of miles away to a doctor who will to the procedure?

Shame on you.

Sep 24, 2012 - 7:19pm
Good for the New York City school system. Now kids won't get the runaround from legislators, moralizing Pharmacists or even parents. You want Plan B? You got it no questions asked.

http://m.yahoo.com/w/legobpengine/news/blogs/sideshow/nyc-schools-handing-morning-pill-without-parental-consent-172010909.html?orig_host_hdr=news.yahoo.com&.intl=US&.lang=en-US

Sep 25, 2012 - 7:45am
OII, all specialists perform the exact same procedures whether they believe them to be necessary or the best choice? BS. We are talking about an ELECTIVE procedure, not life or death.

Why don't you put your money where your mouth is and stop hiding in pharma consulting? You can set up your own abortion clinic and hand out all of the plan B you want. At least then you might command a shard of respect for actually doing something instead simply spewing the constant stream of hot air.

Sep 25, 2012 - 8:10am
MC obviously you have no training in GYN pathology. Many abortions are not elective procedures. Instead the poor woman comes in with, for example a ruptured tubal pregnancy or intrauterine bleeding and impending shock. I guess your solution would be "let's sit down at the computer and Google the nearest abortion clinic".

When you have spent time in the trenches, not on the phone denying reimbursement then come back and tell us how real medicine should be practiced. If I were such a doctor I would have no trouble saying three hail marys then proceed to save the woman's life while you are preparing the eulogy for her funeral.

The real world of medicine functions much differently outside the PBM office.

What is your hang up anyway? Guilt over knocking up your high school girlfriend, even assuming you even had one?

Sep 25, 2012 - 8:16am
dz if you're having trouble deciding who is god, look for the one with the long white beard,long coat, stethoscope in pocket and air of supreme confidence.

As my physician buds say, "sometimes i may be wrong but I'm never in doubt".

Sep 25, 2012 - 8:27am
If you want to run a pharmacy and don't feel comfortable distributing the full range of FDA approved drugs, put up a prominent sign in your shop indicating that you are not a full service pharmacy. People deserve not to get surprised by stuff like that.

You don't want to distribute Plan B. I don't want to do business with an establishment that inconveniences me with religious values that I don't adhere to. Do whatever you want, but be upfront about it. Don't pretend to be one thing to avoid controversy (and possible boycotts) and then surprise me with something else as an expression of your personal beliefs.

Sep 25, 2012 - 9:00am
Imagine if doctors hung John's suggested sign. Then again that's why they are the chosen few, while the pharmacy school graduate annually has to face their families at holiday time and always wishing he could have gotten into medical school so that he could have made them proud. "My son the PharmD? Nah.
Sep 25, 2012 - 10:17am
OII Don't hide behind the fact that some abortions are medically necessary, that's not what is in question here. When you decide to become a practicing physician you can have the repsect of a practicing physician. Until then you are just an ordinary industry hack...the one they prop up in the corner so they can have an MD sign their memos. Had time to brush up on treating anemia yet?

Maybe one of these days I'll get to stamp denied on one of your claims.

Sure governement mandated signs. Both of you would fit in well in Russia.

Sep 25, 2012 - 10:23am
I don't think government mandated signs are necessarily a bad alternative to hiding your business practices from your customers MC.

Or should the customer bear all the inconvenience and burden of your adherence to your ethical standards?

I've been in Russia, and I think the kind of bait-and-switch that you seem to feel a right to practice is much more typical of business there than open disclosure of one's business practices.

Sep 25, 2012 - 10:28am
John, what's to hide?

Do you have Plan B?

No we don't stock that. Other pharmacies have it available.

OK, I'll go to another pharmacy.

God forbid someone might have to get out of their car.

Sep 25, 2012 - 10:39am
Well MC, I think the general principle is that the burden, however small, of your adherence to your moral principles should be borne by you and not me.

Its a little bit like your phone company not offering service to Canada and not telling you in advance. It may not be a huge inconvenience, but telling me in advance gives me the ability to choose a supplier that will address all of my needs.

Sep 25, 2012 - 10:55am
@oii - in this crowd, I'm pretty sure that I found "god" when I look in the mirror - minus the know-it-all attitude because you don't need that mask when you actually ARE "god".

Everybody advertises what's in their store. The only reason someone would omit mentioning that they don't have Plan B is because they want the face to face opportunity - will MC RPh and his cashiers keep their mouths shut about who came in needing the "rescue"?

Being in a small town filled with "gods" who believe in god-knows-what has got to be a nightmare of biblical proportions. And considering how many miles make up USA land, it's probably all too common. Probably should send out buses to help women and children get out of "dodge"....

Sep 25, 2012 - 11:00am
I'll make sure that the MD signs off on the denial of MC's vasectomy reversal. We don't need more paper pushers questioning the judgment of those with four years of medical school, five years of residency and three more years if fellowship just to be denied by someone who spent an extra year in a hospital pharmacy checking the bar codes on the unit dose packaging.
Sep 25, 2012 - 11:04am
Life would get pretty complicated if everywhere you went signs were required stating what isn't sold or provided. Tofu restaurants don't sell milkshakes. Some pharmacies don't sell ANY otc products. My dentist doesn't offer happy endings. No signs for those.

Of course any pharmacy owner that chooses not to offer Plan B would lose those sales and risk a boycott. That's life.

Sep 25, 2012 - 11:10am
What a shame your wasted potential is, OII. All of that schooling and residency to camp out in pharma and fade away? Do you ever think about the lives you could have saved or the good you could have done for humanity? No hospitals or procedures named for you...
Sep 25, 2012 - 12:02pm
With 31 states legally practicing loveless animal husbandry breeding by granting a rapist the "right" to visit his spawn at the rape victim's home, we're not talking about listing msg and tofu and gluten content, are we?
Sep 25, 2012 - 12:30pm
@MC RPh - education reform starts with your "specialty":

http://www.forbes.com/sites/susanadams/2012/04/27/why-do-so-many-doctors-regret-their-job-choice/

Since everyone has a skin suit, so to speak, there needs to be a "bottom" of knowledge established just like there WAS, at one time, for reading, writing and 'rithmentic. That skin suit maintenance education (all 4 years of progressive learning) at the private catholic high school I attended was called "physical education and hygiene". Everyone learned about all the vital organ's basic functions and everyone had to pass a basic test (ie. - the liver does not take in air through the nose) knowledge. Turns out the kids headed to "trades" sometimes did even better than the math geek, and because this talent for "getting it" was discovered, counselors included other career choices in the supportive medical arts - something other than billing clerks.

This is how a sane society makes a commitment to "health care", it establishes a "bottom" of knowledge and from there those who want the career and have the aptitude for it can keep advancing until they hit a level beyond which they just can't advance - who wants rising to your highest level of incompetency (ala made up data) like there is in the corp world of vicious politics and elitism?

As we know, all "clinicians" never stop learning new ways to solve the problems of disease and disaster. You need a little more than prayer sometimes, no?

So how do you rate yourself as a "teacher", MC RPh?

Sep 25, 2012 - 12:36pm
As usual dzieczko I have no idea how what you posted is relevant.
Sep 25, 2012 - 1:47pm
@MC RPH - okay, being subtle is not your strong hand - you started this conversation:

you said to oii, "...What a shame your wasted potential is, OII. All of that schooling and residency to camp out in pharma and fade away? Do you ever think about the lives you could have saved or the good you could have done for humanity? No hospitals or procedures named for you…"

And I merely noted that there's a lot of doctors trying to exit the profession. If a career in pharma is not about saving lives in the millions, well, then, that's a whole other ongoing conversation about pharma that's akin to what is the role of "government" which you do have a lot of opinions about from a "god" perspective, no less.

Sep 25, 2012 - 1:49pm
The future of medical care is going to have to go beyond something other than the admin at the hospital/clinic/doc's office saying, "I'll pray for you" as she hands you the bill.
Sep 25, 2012 - 3:45pm
Under Obamacare that admin will say "I'll PAY for you with the money gleaned from raping the wallet of everybody in the 1%.
Sep 26, 2012 - 11:50am
@oii - why are you constantly b-ching about "obamacare" when all the tricks and traps in that bazzillion page horror were penned by all the interested players - like FOR PROFIT health insurance.

If a "law" was passed by a Big Giant Head, it would be short and to the point like that 3 page stick up note Paulson shoved at the taxpayer in 2008 - "We're taking all your money, land, and whatever else you got squirreled away to pay off the 10 year salary of global mercenaries".

This "tax" to shovel $$$$ to the same gangs - er, health plan, not a tax or wait, it is a tax - is a scheme no one likes.

Let's start with STDs - how about the person who spreads it around PAY for the "health care" of those he infected? Right, we can all find an instance where "lay off my wallet" is what we want to say in regards to the lifestyle choices of others....which means in the final analysis, that health care has been yanked out of the normal flow of "commerce" and "small business" on Main Street. Which means tyranny by misanthropic apparatchiks deciding da or nyet based on the simple formula of how THEY get paid to be apparatchiks: more misery for others = more $$$$ for me me me.

B-tch intelligently, wouldja? I'm not a fan of whipping the slave boy every time I'm in a bad mood...

Sep 26, 2012 - 2:26pm
dz, be glad you don't work in the medical device industry and have to pay the surtax just so that Obama can expand the Medicaid program to more peoplle.

I'm actually surprised I have to remind you cause you're pretty knowledgeable on this stuff, but BHO did a bait and switch by inviting Pharma to help write the law, and as soon as we left the room turned around and whacked us with the highest rebates in history, so that the parasitic 47% who choose to ignore their health can feed off the public mammary gland courtesy of the redistribution of money away from hard honest workers to those who yearn for that lifetime of lactation against that generous nipple of the federal government.

Sep 26, 2012 - 6:34pm
@oii - if you think the Obamas came up with that trick during pillow talk, you are delusional. It was just another "interested player" industry stabbing you in the back...

Health care is in the economic category of "commerce on Main Street". Sure it started with swapping chickens for a cast applied to the broken bone, and until FOR PROFIT HEALTH INSURANCE was concocted, everything was SANE.

Sep 26, 2012 - 9:19pm
dz, when my dad was a struggling young surgeon chickens or other form of barter were perfectly acceptable forms of payment. We could do the same today and avoid the insurance hassle. You want a new liver? Leave your BMW seven series in my driveway and we'll call it even.
Sep 27, 2012 - 11:25am
See, that's the thing, oii. Those workers who are going to need new lungs because of what they were exposed to while doing their job never got close to having the schekles to own that kind of machine.

With for-profit health insurance in the mix, nothing trickles down to Main Street - that's the OBVIOUS math.

Would be nice to see how many "jobs" will be slashed from another layer of siphoning of profit for doing nothing in the way of health care instead of throwing scientists under the bus every Christmas...

So what is going on now is clear, the people who DID contribute to all the advances in health care are being robbed of the opportunity to benefit from the fruits of their labor.

Put another way, I never went to Wyoming or Utah or some other big empty land to ask them for "help" or told them I had the right to pitch my tent on their land and call it Planet Dzieczko like they were able to do under The Homestead Act. So it'll be nice if they STFU and stop telling us in NJ that they'll give us some taxpayer $$$$ to stay in our apartments and die out of sight.

Sep 27, 2012 - 2:27pm
@oii - 14 seconds in - the comment from the bishop about dying in the apartments:

http://www.msnbc.msn.com/id/3096434/#49169798

Sep 27, 2012 - 9:39pm
enjoy oii:

http://rt.com/programs/keiser-report/episode-345-max-keiser/