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Axovant Licenses Two Gene Therapies Aimed at Tay-Sachs and Sandhoff Disease

Days after Axovant announced an end to focusing on a legacy small molecule portfolio in favor of gene therapies, the company reported the licensing of worldwide rights to two gene therapy programs from the University of Massachusetts School of Medicine.

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Merck Buys Animal Health Company Antelliq

Merck & Co. is paying about $2.4 billion to acquire all outstanding shares of Antelliq Group, and is also assuming the digital technology company’s debt of $1.3 billion.

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“A” is for Amplify: CRISPRa Used to Treat Obesity Without Editing the Genome

Researchers at UC San Francisco recently published research in the journal Science describing their use of a modified version of CRISPR gene editing to stimulate the activity of certain genes, resulting in the prevention of severe obesity in mice who had a genetic predisposition to extreme weight gain.

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Amgen Terminates $540 Million Deal with Advaxis

Shares of Advaxis plunged more than 28 percent in premarket trading after the company quietly disclosed that Amgen terminated their collaboration on an immuno-oncology program.

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Biotech Companies Investing in Key Technologies for the Fourth Industrial Revolution

Technology is constantly impacting and changing the way the world works. Greater technological innovations are not only changing the way business operates, but also have a significant impact on employees.

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Study Finds Almost 4% of Cancers Linked to Obesity

A recent study published in CA: A Cancer Journal for Clinicians, a peer-review journal of the American Cancer Society, links excess body weight to approximately 4 percent of cancers worldwide.

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FDA Expands on Biologics and Biosimilars Action Plan, Especially for Diabetes Products

The FDA released two new draft Q&A guidance documents on biosimilar development and two final guidance documents on the same topics, as well as a proposed amendment to the definition of a biological product.

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Lawsuit Charges FDA, NIH With Failing to Follow Established Law for Reporting of Clinical Trial Data

A lawsuit filed by a former official with the U.S. Food and Drug Administration alleges in a lawsuit that the regulatory agency has relaxed reporting requirements for clinical trials.

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The Genome of Giant Tortoise “Lonesome George” Provides Clues to Longevity and Disease Resistance

Researchers published an article in the journal Nature Ecology & Evolution that described preliminary findings of gene variants in Lonesome George – the last of the Pinta Island tortoises of the Galapagos – associated with a strong immune system, efficient DNA repair and cancer resistance.

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Sprayable Gel May Help Fight off Cancer Recurrence After Surgery

A group of researchers with UCLA developed a spray gel that contains immune-stimulating drugs.

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