Bayer in gene therapy collaboration with Mammoth Biosciences
Bayer in gene therapy collaboration with Mammoth Biosciences
January 10, 2022; 3:02 AM EST
FRANKFURT, Jan 10 (Reuters) – Bayer (BAYGn.DE) on Monday struck a partnership deal with Mammoth Biosciences to develop therapeutic tools based on CRISPR/CAS9 gene editing as the German drug maker seeks to widen its cell and gene therapy development efforts.
Unlisted U.S. biotech firm Mammoth will initially receive $40 million from Bayer plus potential milestone payments of more than $1 billion contingent on scientific and commercial achievements.
The initial focus of the collaboration will be liver-based diseases, the companies said in a joint statement on Monday.
Logo and flags of Bayer AG are pictured outside a plant of the German pharmaceutical and chemical maker in Wuppertal, Germany August 9, 2019. REUTERS/Wolfgang Rattay
Mammoth, headquartered in the San Francisco Bay area, was co-founded by Nobel laureate Jennifer Doudna. She shared the 2020 Nobel Prize in Chemistry with Emmanuelle Charpentier for developing the CRISPR/CAS9 gene editing tool.
Among previous steps to build a cell and gene therapy business, Bayer acquired BlueRock Therapeutics and Asklepios Biopharmaceutical in 2019 and 2020, respectively.
In late 2020, it agreed an alliance on anti-tumour immune cell therapies with Atara Biotherapeutics .
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