NKTR-181 shows significantly less abuse potential compared to oxycodone.
More than 400 people – including doctors and nurses – have been charged with defrauding Medicare and other federal healthcare programs of $1.3 billion, with many accused of illegally distributing opioids and other narcotics, the Justice Department said.
A growing number of U.S. states, counties and cities are filing lawsuits accusing drug companies of deceptively marketing opioid painkillers to downplay their addictiveness, but some lawyers say the industry’s highly regulated nature could pose a hurdle to their success.
Spending on prescription medicines in the United States will increase 4-7 percent through 2021, reaching $580 billion to $610 billion, according to a report released by QuintilesIMS Holdings.
Mallinckrodt Plc agreed to pay $35 million to resolve U.S. probes into its monitoring and reporting of suspicious orders of controlled substances.
U.S. Democratic Senator Claire McCaskill seeking details from the nation’s top opioid drugmakers on their sales and marketing practices.
Nektar Therapeutics said its experimental opioid succeeded in a key late-stage study.
Only some doses of Trevena’s experimental opioid painkiller were found as effective as morphine in two late-stage studies, though the drug met its main study goals.
Amphastar Pharmaceuticals Inc. said the U.S. Food and Drug Administration had rejected its application to market an intranasal version of the emergency opioid-overdose treatment, naloxone.