The U.S. Food and Drug Administration removed a boxed warning about increased risk of leg and foot amputations with Johnson & Johnson’s diabetes drug Invokana.
Janssen Presents Landmark Data From Invokana Study
Black Box Warning, Cardiovascular Deaths, Cardiovascular Events, Chronic Kidney Disease, Clinical Data, Clinical Trials, Diabetes, FDA, Glycemic Control, Kidney Failure, Lower limb amputations, R&D, SGLT2 Inhibitors, Supplemental New Drug Application (sNDA), Type 2 DiabetesJanssen’s Invokana became the only medicine in nearly 20 years and the first diabetes medicine ever to demonstrate a reduction in progression to end-stage renal failure in T2D patients with CKD.