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The Pulse of the Pharmaceutical Industry

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Pfizer’s revenue, profit beat as vaccine sales rise

Pfizer Inc on Tuesday reported better-than-expected second-quarter profit and revenue, helped by strong demand for its pneumonia vaccine and new breast cancer drug, sending its shares up 1 percent. The largest U.S. drugmaker, which raised its full-year earnings forecast, said revenue from its global vaccines unit rose 44 percent to $1.58 billion. The unit, which […]

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Merck raises forecast on strong sales of diabetes, cancer drugs

Merck & Co Inc (MRK.N) reported a better-than-expected quarterly profit and boosted its full-year earnings forecast as demand for its diabetes and cancer drugs increased. The company also said it expects to reap benefits from its $8.4 billion purchase of Cubist Pharmaceuticals, the maker of blockbuster antibiotic Cubicin. Cubicin sales for the second quarter were […]

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The FDA Approves A Potent And Pricey Cholesterol-Lowering Shot

The Food and Drug Administration has approved Praluent, a new medicine to lower cholesterol in people who have established heart disease, for people whose risk of a heart attack or stroke is not being adequately controlled by existing drugs called statins. It might be a big step in the battle against heart disease – and […]

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Valeant profit beats estimates as U.S. sales stay strong

Drugmaker Valeant Pharmaceuticals International Inc (VRX.TO) (VRX.N) reported a better-than-expected quarterly profit, helped by strength in its dermatology business in the United States. The company also raised its earnings and revenue forecast for the year to reflect sales of recently acquired Salix Pharmaceuticals’ irritable bowel syndrome drug, Xifaxan. The U.S. Food and Drug Administration approved […]

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Abbott profit beats estimates on higher sales of generics

Abbott Laboratories Inc reported a slightly better-than-expected quarterly profit, helped by higher sales of its branded generics. Sales at Abbott’s three largest businesses – nutritional products, diagnostic products and pharmaceutical products – rose in the second quarter, helping the company reaffirm its full-year profit forecast. The acquisition of Chile’s CFR Pharmaceuticals S.A. in September helped […]

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Celgene Strikes Again, Extends Epizyme Pact By Three Years in Deal Worth $620 Million

Cambridge, Mass.-based Epizyme, Inc. (EPZM), announced today that it amended its agreement with Celgene Corporation for at least three more years. The original agreement, signed three years ago, was for EPZ-6438 (tazemetostat) for the treatment of non-Hodgkin lymphoma patients and patients with INI1-deficient solid tumors, and EPZ-5676 (pinometostat), an inhibitor of DOT1L for the treatment […]

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Novartis wins early U.S. approval for major new heart drug

Novartis AG on Tuesday won U.S. approval for its keenly awaited new heart failure drug Entresto earlier than expected, boosting hopes for a medicine tipped by analysts to reap billions of dollars in annual sales. The Swiss drugmaker had previously said U.S. approval was likely in August. The U.S. Food and Drug Administration said in […]

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Vertex’s $259,000 Cystic Fibrosis Drug Approved

The U.S. Food and Drug Administration approved Vertex Pharmaceutical Inc.’s cystic-fibrosis drug Orkambi, which could treat as many as 8,500 patients in the U. S. — but at a whopping annual wholesale cost of $259,000 per patient. The drug, a twice-daily oral tablet for patients 12 years and older, expands the company’s reach in the […]

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Exclusive: Hospira wins French biosimilar drug tender at 45 percent discount

A major French hospital group has chosen a cheap copycat version of a top-selling drug for treating its patients with rheumatoid arthritis, Crohn’s disease and psoriasis in a victory for a new type of medicine known as biosimilars.    In a document seen by Reuters, the central purchasing agency for the Assistance Publique – Hôpitaux de […]

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Genentech’s Ocrelizumab Wows in Late Stages and Eyes $18 Billion MS Market

South San Francisco, Calif.-based Genentech (RHHBY) announced today that its clinical studies of ocrelizumab compared to interferon beta-1a (Rebif) in relapsing multiple sclerosis (MS) met their primary and major secondary endpoints.   Two Phase III studies are being conducted, OPERA I and OPERA II. The primary endpoint of both studies was annualized protocol-defined relapse rate […]

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