Magenta Therapeutics is reducing the company’s workforce by 14 percent in a revised operating plan to prioritize research and development.
AstraZeneca said the company’s Enhertu cancer drug has been shown to significantly help women suffering from a type of breast cancer that leaves them with poor treatment options, opening the door to a much larger potential patient group.
Mersana Therapeutics signed a research and licensing deal with Janssen Biotech to access each other’s proprietary technology in discovering new antibody-drug conjugates (ADCs) for three cancer targets.
Seagen (formerly known as Seattle Genetics) forged an exclusive licensing agreement with China’s RemeGen to develop and commercialize disitamab vedotin, a novel HER2-targeted antibody drug conjugate (ADC).
Daiichi Sankyo and AstraZeneca reported positive topline data from their head-to-head DESTINY-Breast-03 Phase III trial for Enhertu versus trastuzumab emtansine (T-DM1) in patients with HER2 positive metastatic breast cancer.
Bristol Myers Squibb and Eisai forged a strategic collaboration that could be worth nearly $2.5 billion to jointly develop MORAb-202, an antibody drug conjugate (ADC) to be used against certain solid tumors across several different cancer types.
UK Variant Not as Lethal as Originally Reported
Antibody-Drug Conjugates (ADCs), Breast Cancer, Brown Fat Cells, Cancer Immunology Research, COVID-19 Deaths, COVID-19 Variant B.1.1.7, Covid-19 Variants, Fat Cells, Harvard Medical School, Hospitalized COVID-19 Patients, Immune Cells, Lancet Infectious Diseases, Lancet Public Health, Massachusetts General Hospital, MD Anderson Cancer Center, Osteosarcoma, SARS-CoV-2 virus, Skin Cancer, T-Cells, The Ohio State University Wexner Medical Center, Tumors, WuhanA new study by researchers at the University College London (UCL) published in Lancet Infectious Diseases finds that although the U.K. variant of SARS-CoV-2 known as B.1.1.7 is more transmissible than the wild-type, original Wuhan strain, it is likely not more deadly.
Boehringer Ingelheim is paying 1.18 billion euros ($1.5 billion) for Swiss-based NBE Therapeutics as the German drugmaker is adding pipeline candidates including a drug in early trials against triple-negative breast cancer and lung cancer.
BioSpace Global Roundup: Ipsen Wins Fast Track Designation for Cancer Drug and More
3D, Antibody-Drug Conjugates (ADCs), Business, Clinical Trials, Collaborations, Coronavirus Disease 2019 (COVID-19), Data, E. Coli, Fast Track Designation, FDA, Gene Editing, Joint Ventures, Licensing, Metastatic pancreatic cancer, Neurological Disorders, R&D, Series A, Small cell lung cancer, Staphylococcus aureus infections, Therapeutics, Ulcerative Colitis, VaccinesParis-based Ipsen secured Fast Track designation from the U.S. Food and Drug Administration for Onivyde (irinotecan liposome injection) for study patients with small cell lung cancer (SCLC) who progressed following a first-line platinum-based regimen.
Urovant’s Irritable Bowel Drug Fails in Phase II; Genmab Abandons Cancer Drug
Abdominal Pain, Antibody-Drug Conjugates (ADCs), Biomarkers, Business, Cancer, Clinical Trials, Irritable Bowel Syndrome with Diarrhea (IBS-D), Monoclonal Antibodies, Product Pipelines, R&D, Shares, Small Molecules, Solid Tumors, Topline DataUrovant Sciences and Genmab reported disappointing clinical trial announcements.