For the first time, researchers tested CRISPR gene editing inside a person’s body. Allergan and Editas Medicine treated the first patient in the BRILLIANCE clinical trial of AGN-151587 at Oregon Health & Science University (OHSU) Casey Eye Institute. The therapy is being tested for treatment of Leber congenital amaurosis 10 (LCA10), an inherited type of blindness caused by mutations in the centrosomal protein 290 (CEP290) gene.