Severe obesity may weaken the effectiveness of COVID-19 vaccines in those who have never been infected with the coronavirus, according to a small Turkish study. Additionally, South African researchers have found infection with the Omicron variant of the coronavirus can significantly improve the immune system’s ability to protect against other variants, but only in people who have been vaccinated.
Using Assessment Tools to Determine the Validity of Non-Randomized Studies
Analysis, Body Mass Index (BMI), Clinical Trials, Diabetes, FDA/Regulatory, IQVIA, National Institute for Health and Care Excellence (NICE), Nonrandomized studies (NRS), Patients, R&D, Randomized Controlled Trials (RCTs), Real world evidence, ResearchersAs real world evidence (RWE) becomes a more prevalent resource for confirming and expanding product benefit-risk profiles, non-randomized studies (NRS) are emerging as a valuable generator of real world data (RWD). Joan Largent – Senior Director, Epidemiology and Outcomes Research at IQVIA – discusses the findings of her recent study and how researchers can utilize assessment tools for their ability to accurately assess NRS validity.