More than half of the first 21 brains donated to the Australian Sports Brain Bank by former athletes showed signs of chronic traumatic encephalopathy (CTE), a degenerative disease caused by repeated concussions, a study showed.

Researchers have unlocked a key mechanism behind the genetic variant which could prove hopeful for new treatments for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).

Dr. Ann McKee of Boston University studies the brains of deceased football players at the world’s largest brain bank, hoping to learn about the long-term impact of repeated head traumas for people ranging from professional athletes to victims of domestic abuse.