Novartis is expanding the Swiss pharma giant’s optogenetics portfolio with the acquisition of gene therapy company Arctos Medical.

According to a California WARN notice, Sanofi is shuttering Principia Biopharma’s laboratories in San Francisco and laying off about three dozen employees after the Phase III PEGASUS trial failure of rilzabrutinib for pemphigus.

Fully integrated biopharmaceutical solutions organization Syneos Health announced the acquisition of StudyKIK, a leading technology-enabled clinical trial recruitment and retention company.

Florida-based AzurRx BioPharma is bolstering the company’s gastrointestinal disease pipeline with the $229 million acquisition of First Wave Bio and its small molecule therapeutics for auto-immune inflammatory bowel diseases (IBD) and other serious conditions.

Roche bolstered the Swiss pharma giant’s diagnostics capabilities by acquiring the company’s long-term partner, TIB Molbiol. The procurement will expand Roche’s PCR-test portfolio capabilities in the ongoing fight against existing and emerging infectious diseases, including new Covid-19 variants of interest. 

Google’s Verily snapped up Raleigh, N.C.-based SignalPath and the company’s clinical trial management system that is expected to support its own clinical trial and evidence-based platform known as Baseline.

Bayer AG is buying Vividion Therapeutics, a San Diego-based company that focuses on drug development using protein surface screening, in a $2 billion deal.

Amgen is snapping up privately held Teneobio and the company’s class of biologics dubbed Human Heavy-Chain Antibodies in a deal that could total $2.5 billion.

In PerkinElmer’s largest purchase ever, the Massachusetts-based company is dropping a massive $5.25 billion in cash and stock to buy the biomedical research tool company BioLegend. 

EVERSANA, a pioneer of next-generation commercial services to the global life sciences industry, announced the acquisition of Accelera Canada and its partner companies Patient Access Solutions, Podium Strategic Partners Inc. and Advocacy Solutions.