Rising COVID-19 cases are driving up the use of therapeutics, with Pfizer Inc.’s oral antiviral treatment Paxlovid seeing a 315 percent jump over the past four weeks, U.S. health officials said on May 17.

New York, New Jersey and Connecticut urged their residents to not travel between the three states as the U.S. Northeast sees a rise in Covid-19 cases, while California said major theme parks including Disneyland would not be opening anytime soon.

New York state sued Purdue Pharma LP, accusing the OxyContin maker of widespread fraud and deception in the marketing of opioids, and contributing to a nationwide epidemic.