Johnson & Johnson’s one-dose Covid-19 vaccine appeared safe and effective in trials, the U.S. Food and Drug Administration said, paving the way for approval for emergency use as soon as Feb. 26.

Clover Biopharmaceuticals raised a $230 million series C round co-led by GL Ventures and Temasek, which will push the Chinese fusion protein company’s Covid-19 vaccine into Phase II/III testing and production planning.

Public Health England (PHE) published real-world analyses of people in the U.K. who had received the first shot of the Pfizer-BioNTech Covid-19 vaccine, with the data – which were published in The Lancet – showing that there was a decrease of about 70 percent in infections among healthcare workers after the first shot.

The U.S. Food and Drug Administration issued new guidance for vaccine makers as the regulatory agency is preparing for the possibility of needing to approve Covid-19 booster shots against variants of the SARS-CoV-2 virus.

Drugmakers should test any Covid-19 vaccines that have been retooled to combat new variants of the coronavirus in clinical trials designed to track the immune response of hundreds of subjects, which could take months, U.S. regulators said on Feb. 22.

GlaxoSmithKline and Sanofi started a new clinical trial of their protein-based Covid-19 vaccine candidate, reviving their efforts against the pandemic after a setback in December delayed the shot’s launch.

Novavax announced a Memorandum of Understanding (MOU) with Gavi, the Vaccine Alliance, to provide 1.1 billion doses of the company’s Covid-19 vaccine candidate NVX-CoV2373 for the COVAX Facility.

The United States reported a 23% drop in new cases of Covid-19 and a 16% fall in the number of people hospitalized with the virus for the week ended Feb. 14, with both figures declining for a fifth week in a row.

Australia’s second most populous state Victoria entered a five-day lockdown on Feb. 13 as authorities raced to prevent a third wave of Covid-19 cases sparked by the highly infections UK variant.

A molecular test from Becton Dickinson that detects viruses that cause Covid-19 as well as influenza and produces result in 2-3 hours was given emergency use authorization by the U.S. health regulator.