Another wave of states prepared to ease coronavirus restrictions on U.S. commerce this week, despite health experts warning there is still too little diagnostic testing, while the White House forecast a staggering jump in the nation’s monthly jobless rate.

Americans spent a glum Easter Sunday largely confined to their homes by the still-raging coronavirus pandemic as the U.S. death toll neared 22,000, with more than half a million confirmed cases nationwide.

AstraZeneca filed a Worker Readjustment and Retraining Notification Act (WARN) notice with the State of Colorado, indicating plans to lay off 210 people in Boulder and Longmont.