The number of Covid-19 deaths in the United States crossed 250,000, according to a Reuters tally, as a third coronavirus wave brings a fresh surge in infections and puts immense strain on the healthcare system.

The number of new Covid-19 cases rose 11% in the United States last week compared to the previous seven days, with infections spreading rapidly in the Midwest, which reported some of the highest positive test rates, according to a Reuters analysis.

Covid-19 shattered records for new cases in the U.S. Midwest, straining hospitals, and will darken New York’s Broadway theaters until June, a decision the Actors’ Equity Association union called “difficult but responsible.”

The number of tests coming back positive for Covid-19 is topping 25% in several states in the U.S. Midwest as cases and hospitalizations also surge in the region, according to a Reuters analysis.

The number of novel coronavirus cases in the United States topped 7 million – more than 20% of the world’s total – as Midwest states reported spikes in Covid-19 infections in September, according to a Reuters tally.

The number of new cases of the novel coronavirus reported in the United States fell 15 percent last week from the previous seven days, and deaths fell for a fourth week in a row, according to a Reuters analysis.

Coronavirus cases are rising in 22 of the 50 U.S. states, according to a Reuters analysis, a worrisome trend on a Labor Day holiday weekend traditionally filled with family gatherings and parties to mark the end of summer.

U.S. cases of the novel coronavirus surpassed six million as many states in the Midwest reported increasing infections, according to a Reuters tally.