The United States surpassed Italy on Saturday as the country with the highest reported coronavirus death toll, recording more than 20,000 deaths since the outbreak began, according to a Reuters tally.

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New York is nearing a plateau in the number of coronavirus patients hospitalized, a sign of optimism even though the number of the deaths in the state hit a single-day high, Governor Andrew Cuomo said.

The coronavirus has been a far deadlier threat in New Orleans than the rest of the United States, with a per-capita death rate almost three times that of New York City. Doctors, public health officials and available data say the Big Easy’s high levels of obesity and related ailments may be part of the problem.

The number of U.S. coronavirus infections climbed above 86,000 on Friday as New York, New Orleans and other hot spots faced a surge in hospitalizations and looming shortages of supplies, staff and sick beds.

As a critical industry during the COVID-19 pandemic, biopharma companies are expected to remain in operation – but with a skeleton staff. Anticipating stay-at-home mandates, life sciences companies and labs in especially hard-hit regions had already begun preparing.

New York will launch a clinical trial using blood plasma from patients who have recovered from COVID-19, the disease caused by the novel coronavirus.

U.S. states pleaded with the Trump administration to coordinate a national response to the coronavirus outbreak, saying patchwork measures enacted by state and local authorities were insufficient to confront the coast-to-coast emergency.

A highly anticipated trial pitting New York state against McKesson Corp., Johnson & Johnson, CVS Health Corp. and others for allegedly fueling the opioid epidemic was postponed due to the coronavirus outbreak, according to the court.

Health officials in Washington state said a nursing home resident died after contracting coronavirus, while New York’s governor confirmed his state’s first positive case, as the virus moved out of its West Coast foothold.