Wisconsin and other states in the U.S. Midwest and beyond are battling surges in Covid-19 cases, with new infections and hospitalizations rising to record levels in an ominous sign of a nationwide resurgence as temperatures get colder.

Covid-19 shattered records for new cases in the U.S. Midwest, straining hospitals, and will darken New York’s Broadway theaters until June, a decision the Actors’ Equity Association union called “difficult but responsible.”

Six states reported record numbers of hospitalized Covid-19 patients, including Wisconsin, where officials issued a new order limiting the size of indoor public gatherings.

New cases of Covid-19 rose in 27 out of 50 U.S. states in September compared with August, led by an increase of 111% in Wisconsin, according to a Reuters analysis.

The number of tests coming back positive for Covid-19 is topping 25% in several states in the U.S. Midwest as cases and hospitalizations also surge in the region, according to a Reuters analysis.

The number of novel coronavirus cases in the United States topped 7 million – more than 20% of the world’s total – as Midwest states reported spikes in Covid-19 infections in September, according to a Reuters tally.

Seven U.S. states reported record one-day increases in Covid-19 cases so far in September even as the average daily number of new infections is falling nationally.

The number of new cases of the novel coronavirus reported in the United States fell 15 percent last week from the previous seven days, and deaths fell for a fourth week in a row, according to a Reuters analysis.

Several states in the U.S. Midwest and Northeast have seen new Covid-19 cases increase for two weeks in a row, though nationally both new infections and deaths last week remained on a downward trend, a Reuters analysis showed.

U.S. cases of the novel coronavirus surpassed six million as many states in the Midwest reported increasing infections, according to a Reuters tally.