Zafgen Inc said the U.S. Food and Drug Administration was putting a late-stage study testing its experimental obesity drug on complete hold after a second patient died during the trial. The company’s shares fell 7.4 percent to $5.81 in extended trading after closing down 60 percent on Wednesday. A complete clinical hold is an order […]

India will fully fund its AIDS control program federally, the health minister said on Tuesday, restoring support months after it was criticized for slashing its contribution and asking individual states to fill the gap.   India’s globally-lauded AIDS program has been in disarray since last year due to payment delays that worsened after Prime Minister […]

Merck & Co said an independent data monitoring committee recommended that the drugmaker continue a study of its experimental cholesterol drug, anacetrapib. The recommendation comes a month after Eli Lilly & Co stopped testing a similar cholesterol drug, belonging to a class of drugs called CETP inhibitors. Merck said on Friday that the committee reviewed […]

Eli Lilly’s new diabetes drug Jardiance significantly cut the risk of heart-related death and hospitalization for heart failure in patients with type 2 diabetes who are at high risk for serious heart problems, according to data from a large study presented on Monday. The 3-year trial of more than 7,000 patients caused a sensation in […]

An experimental heart failure drug being developed by Cytokinetics Inc and Amgen Inc demonstrated several beneficial cardiac function effects in a midstage clinical trial, according to data presented on Sunday. The trial of 448 patients with chronic heart failure already receiving optimal care tested a twice-a-day oral version of the drug, omecamtiv mecarbil, against a […]

Zafgen Inc said the U.S. Food and Drug Administration had put a late-stage trial of its obesity drug on partial hold, two days after the drug developer reported the death of a patient during the study. Zafgen’s stock was down about 24 percent at $15.92 in light premarket trading. Zafgen said it still expects to […]

The U.S. Food and Drug Administration on Tuesday issued warning letters to five distributors of pure powdered caffeine, as the federal agency stepped up efforts to curtail ingestion of the stimulant in its pure form. The drug regulator had in 2014 issued a consumer advisory warning of the risk to taking pure powdered form of […]