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Alzheimer’s Disease Insight Report: Current Therapies, Drug Pipeline and Outlook

In honor of November being Alzheimer’s Awareness month, BioSpace evaluated the current therapies, drugs in the pipeline and disease outlook.

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Study shows Apple devices in combo with apps could identify dementia

Drugmaker Eli Lilly and Company said early results from a study suggest that Apple Inc. devices, including the iPhone, in combination with digital apps could differentiate people with mild Alzheimer’s disease dementia and those without symptoms.

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Eisai Starts Phase III Trials for Second Alzheimer’s Drug After First’s Failure

Eisai Co. Ltd. initiated Phase 3 clinical trials of the Alzheimer’s treatment BAN2401 one day after the Japanese drugmaker and U.S. partner Biogen Inc. scrapped studies for the Alzheimer’s drug aducanumab.

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In What Could Be an Alzheimer’s Breakthrough, UCLA Scientists Link Specific Gene Mutations to Dementia

Researchers with the University of California, Los Angeles (UCLA) Health Sciences have identified two major groups of genes that, when mutated, results in overproduction of the tau protein, at least in mice.

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New Report Expresses Optimism Over Current State of Alzheimer’s Drug Development

Noting that from 1998 to 2017 there were about 146 failed shots at developing drugs for Alzheimer’s disease, the Pharmaceutical Research and Manufacturers of America (PhRMA) released a report on the state of the industry.

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Allergan and Sosei Halt Alzheimer’s Study

Allergan and the company’s development partner Sosei Group voluntarily suspended clinical trials of HTL0018318 in Alzheimer’s and other types of dementia because of safety problems.

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Roche gets breakthrough status for Alzheimer’s test Elecsys

The U.S. Food and Drug Administration granted Roche an accelerated review for the Swiss drugmaker’s Elecsys product used to diagnose Alzheimer’s disease.

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Bill Gates backs $30 million push for early Alzheimer’s diagnostics

Billionaire Bill Gates and Estée Lauder Cos chairman emeritus Leonard Lauder said they will award $30 million over three years to encourage development of new tests for early detection of Alzheimer’s disease.

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Biogen, Eisai’s AD succeeds in mid-stage study

Japanese drugmaker Eisai Co. and Biogen Inc. said the final analysis of a mid-stage trial of their Alzheimer’s drug showed positive results for patients who received the highest dose.

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Dementia venture fund raises $350 million to hunt new drugs

A venture capital fund dedicated to finding new ways to prevent and treat dementia raised $350 million, far exceeding the initial target of $200 million set on its launch in 2015.

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