Oklahoma Attorney General Mike Hunter’s $17 billion lawsuit is the first to go to trial of more than 2,000 actions by state and local governments accusing opioid manufacturers of contributing to an epidemic linked to a record 47,600 overdose deaths in 2017, according to the U.S. Centers for Disease Control and Prevention.

Five U.S. states filed lawsuits accusing Purdue Pharma LP of illegally marketing and selling opioids, including OxyContin.

Opioid use has reached crisis proportions not only in the United States but also in Canada and some European countries, as prescription opioid painkillers have become much more common, the OECD club of wealthy nations said.

The founder of Insys Therapeutics Inc. became the highest-ranking pharmaceutical executive to be convicted in a case tied to the U.S. opioid crisis, when he and four colleagues were found guilty of participating in a scheme to bribe doctors to prescribe an addictive painkiller.

Drug distributor McKesson Corp. agreed to pay $37 million to resolve a lawsuit by the state of West Virginia seeking to hold the company responsible for contributing to the opioid epidemic, the state’s attorney general said.

U.S. President Donald Trump touted progress in the fight against opioid abuse and promised to hold drugmakers accountable for their part in the crisis, a day after his administration brought its first related criminal charges against a major drug distributor and company executives.

President Donald Trump is expected to tout his fight against opioid abuse in remarks in Atlanta a day after his administration brought its first related criminal charges against a major drug distributor and company executives.

Oklahoma’s attorney general dropped all but a single claim against Johnson & Johnson and Teva Pharmaceutical Industries Ltd. in a closely watched lawsuit alleging the drugmakers helped fuel the U.S. opioid epidemic.

China will expand the range of fentanyl-related substances the country defines as controlled narcotics, a Chinese security official said, blaming U.S. culture for abuse of the drug.

Purdue Pharma LP fraudulently transferred funds to members of the wealthy Sackler family who control the OxyContin maker despite knowing the company faced major liabilities that had made it already insolvent, New York’s attorney general alleged.