Researchers at the University of Pennsylvania and Children’s National Hospital in Washington, D.C., utilized a hybrid approach that combined gene therapy with gene editing to treat a rare genetic disease in animal models.

Researchers with the Abramson Cancer Center of the University of Pennsylvania, led by Carl June, published results from the first U.S. Phase I trial of CRISPR-Cas9-edited T-cells in humans with advanced cancer.

CRISPR Therapeutics and Vertex Pharmaceuticals announced positive interim data from the first patients in the companies’ Phase I/II clinical trials of the CRISPR/Cas9 gene-editing therapy CTX001.

For Halloween, BioSpace collected six tales of thrills and chills from the pharma and biotech industries that will surely have you covering your eyes in terror.

Yale University researchers developed a new system dubbed Multiplexed Activation of Endogenous Genes as Immunotherapy (MAEGI) that hunts down cancer cells.

Researchers at the University of California, San Diego (UCSD) School of Medicine have identified a key switch that has the potential to eliminate dormant HIV reservoirs.

Trucode Gene Repair Inc. emerged from stealth mode with $34 million in financing to bolster the biotech startup’s triplex gene-editing technology.

Researchers with the Salk Institute developed a new type of gene editing called SATI that may provide the option of editing numerous gene mutation diseases such as Huntington’s disease and the rare premature aging syndrome, progeria.

Three U.S. senators introduced a resolution in support of a moratorium and other limits on gene editing embryos.

GlaxoSmithKline struck a research deal with the early pioneers of a prominent gene-editing technology at the University of California.