Eli Lilly and Co has stopped a late-stage trial of its closely watched cholesterol treatment after the drug proved ineffective, sending its shares as much as 9 percent lower and hitting the stock of Merck & Co Inc, which is developing a similar medicine. “Today’s news is a negative for Lilly and we anticipate that […]

Heart device maker St. Jude Medical Inc received a warning letter from the U.S. Food and Drug Administration, which said that various devices of the company manufactured at its Atlanta plant are adulterated. The health regulator in a letter dated Sept. 30 also warned that the company’s manufacturing, packing, storage and installation practices “are not […]

Democratic lawmakers on Monday attacked “massive” price increases of two heart drugs by Canada’s Valeant, fueling a rout in drugmaker shares on worries of a government and insurer clampdown on U.S. drug prices. All 18 Democratic members of the House of Representatives Committee on Oversight and Government Reform urged their chairman to subpoena Valeant Pharmaceuticals […]

(Reuters Health) – According to a reanalysis of the original data from a 2001 study of paroxetine (Paxil) for teens with major depression, the drug was not effective and led to serious side effects, which is not how the results were presented 14 years ago. “There have been warnings about paroxetine for a long time,” […]

GlaxoSmithKline’s inhaled medicine Breo failed to prolong life in patients with chronic respiratory disease in a high-stakes clinical trial of 16,500 people, torpedoing hopes of a sales boost for the drug. Shares in Britain’s biggest drugmaker fell 1.5 percent on Wednesday, lagging a strong London market, in reaction to the news announced by the company […]

Two studies have identified a gene associated with potentially fatal abnormal heart rhythms, device maker Medtronic Plc said on Monday. The studies evaluated genetic information to identify gene abnormalities that may be associated with heart rhythms that could cause sudden cardiac death, the company said. Sudden cardiac death (SCD) is an unexpected death caused by […]

CVS Health Corp, the second-largest manager of drug benefit plans for U.S. employers and insurers, asked heart specialists on Monday to revamp guidelines for treating patients with high cholesterol after the launch of new, expensive medications. The unusual move is the latest salvo in the war on escalating U.S. healthcare costs, with insurers using aggressive […]