Ironwood Pharmaceuticals initiated an internal organizational restructuring that includes cutting up to 100 full-time employees from payroll following a review of unblinded data from the company’s Phase III trials for IW-3718-302, which show that the drug failed to reduce the severity of heartburn in patients with refractory gastroesophageal reflux disease (GERD).
The FDA found high levels of the same type of carcinogen that led to the recall of some hypertension and heartburn medications in some of the extended-release version metformin drugs that had been tested.
More drugs are being assessed as potential treatments against the pandemic as the battle against COVID-19 continues. Researchers in New York are seeking to determine if the active ingredient in an over-the-counter heartburn medication will have any impact on the disease.
The U.S. Food and Drug Administration is requesting makers of all versions of the heartburn drug Zantac to remove the products from the market immediately due to the presence of a probable carcinogen.
RedHill Biopharma Ltd.’s three-drug combination therapy to treat Helicobacter pylori bacterial infections was approved by the U.S. Food and Drug Administration.
The U.S. Food and Drug Administration is investigating whether the popular heartburn drug Zantac causes carcinogens to form in the bodies of users, in an effort to fully understand the risks posed by the already recalled drug, the agency’s spokesman said.
GlaxoSmithKline Plc is recalling the company’s heartburn medicine Zantac as a “precautionary measure” due to a probable cancer-causing impurity in the drug, Britain’s medicines watchdog said.
The FDA found “unacceptable levels” of a cancer-causing impurity in limited testing using low-heat method of samples of heartburn medicines such as Zantac containing the ingredient ranitidine.
Novartis AG’s Sandoz unit is halting distribution of the company’s versions of the product commonly known as Zantac in all of the Swiss drugmaker’s markets, including the United States and Canada, after contaminants were found in the heartburn drug.
Heartburn sufferers who do not feel better with standard treatment, but who have no detectable reflux, tend to have greater distress and worse quality of life, according to a new study.