The number of novel coronavirus cases in the United States topped 7 million – more than 20% of the world’s total – as Midwest states reported spikes in Covid-19 infections in September, according to a Reuters tally.

Coronavirus cases are rising in 22 of the 50 U.S. states, according to a Reuters analysis, a worrisome trend on a Labor Day holiday weekend traditionally filled with family gatherings and parties to mark the end of summer.