Autoimmune inflammation

AstraZeneca Hits Roadblock in Nasal Polyps as FDA Wants More Data

AstraZeneca, Autoimmune inflammation, Chronic rhinosinusitis with nasal polyps (CRSwNP), Clinical Trial Endpoints, Clinical Trials, Complete Response Letter, New Indications, Orphan Drug Designation, Primary Endpoints, R&D, Supplemental Biologics License Application (sBLA)

AstraZeneca’s Fasenra (benralizumab) hit a roadblock in attempting to expand the medicine’s indications when the U.S. Food and Drug Administration issued a Complete Response Letter for chronic rhinosinusitis with nasal polyps (CRSwNP).

March 14, 2022/by BioSpace

Researchers Working to Understand Why Some Patients with Autoimmune Diseases Develop Diabetes Instead of Arthritis

Arthritis, Autoimmune Diseases, Autoimmune inflammation, Beta cells, Diabetes, Genes, Immune Cells, Inflammatory Bowel Disease, Insulin, Multiple Sclerosis, National Institutes of Health, Nature Genetics, Pancreatic beta cells, Pluripotential cells, Researchers, Rheumatoid Arthritis (RA), Systemic Lupus Erythematosus (SLE), Type 1 Diabetes

Recently published research in the journal Nature Genetics found significant insight into this question: Why does a patient with an autoimmune disease become a type 1 diabetic rather than have rheumatoid arthritis?

November 21, 2019/by BioSpace