Staff reviewers of the U.S. Food and Drug Administration have raised questions about the safety of AstraZeneca Plc’s gout treatment. Reviewers pointed to higher death rates, cardiovascular issues and kidney-related side effects in patients who took the drug, lesinurad, a preliminary review published on Wednesday showed. Industry analysts forecast annual sales of the drug to […]

Johnson & Johnson’s Stelara was significantly better than placebo at inducing clinical response and remissions in patients with moderate to severe Crohn’s disease, according to data from a late stage trial, providing ammunition for a potential expanded approval of the medicine. Stelara, a biotech medicine that blocks inflammation, is approved to treat the skin condition […]

Eli Lilly and Co and Incyte Corp said their experimental drug was found to be more effective in treating rheumatoid arthritis than a commonly prescribed medicine, in a late-stage study. The drug, baricitinib, reduced signs and symptoms of the inflammatory disorder better than the decades-old treatment, methotrexate, after 24 weeks, the companies said on Tuesday. […]

Some leukemia patients who had exhausted other treatment options have no trace of the disease more than four years after being treated with an experimental type of therapy called CAR T cells in a small pilot study at the University of Pennsylvania. The 14-patient study, which began in the summer of 2010, enrolled patients who […]

Mental health problems like anxiety and depression may partly explain why people with rheumatoid arthritis have an increased risk of cardiovascular disease, according to a new study. Researchers linked anger, anxiety, depressive symptoms, job stress and low social support to increasing risk of hardening of the arteries, or atherosclerosis, for people with rheumatoid arthritis (RA). […]

Children who eat certain types of fish may be less likely to develop nasal allergies, according to a study from Sweden. Researchers studied what children ate at age eight and then monitored whether they developed nasal inflammation due to allergies or colds by age 16. Regular consumption of oily fish like salmon was linked a […]

Xoma Corp said its lead drug failed to meet the main goal of reducing inflammation in the eye in a late-stage study, sending its shares plunging 80 percent in premarket trading. The drug developer said on Wednesday the compound, gevokizumab, was not better than a placebo in reducing the risk of inflammation in patient’s blood […]

Coffee drinkers in a long-term study were about half as likely to develop type 2 diabetes as those who didn’t drink coffee, and researchers think an inflammation-lowering effect of the beverage might be the key. “Extensive research has revealed that coffee drinking exhibits both beneficial and aggravating health effects,” said Demosthenes B. Panagiotakos of the […]