The number of new Covid-19 cases in the United States last week rose 24% to more than 485,000 while the number of tests performed rose 5.5%, according to a Reuters analysis of state and county reports.

The United States saw the country’s highest-ever number of new Covid-19 cases in the past two days, keeping the pandemic a top election issue as Vice President Mike Pence travels the U.S. to campaign despite close aides testing positive.

U.S. infectious disease expert Anthony Fauci said it would be clear whether a Covid-19 vaccine was safe and effective by early December, but that more widespread vaccination would not be likely until later in 2021.

The United States broke the country’s daily record for new coronavirus infections with a reported 84,218 new cases due to outbreaks in virtually every part of the country, according to a Reuters tally.

The United States is likely to have enough safe and effective Covid-19 vaccines available to inoculate the most vulnerable Americans by the end of 2020, Health and Human Services Secretary Alex Azar said.

Students in Boston’s public schools will shift to remote learning due to the rising Covid-19 infection rate in the city that was ravaged by the pandemic in the spring.

Brazilian health authority Anvisa said a volunteer in a clinical trial of the Covid-19 vaccine developed by AstraZeneca and Oxford University died, stating it had received data from an investigation into the matter.

Global coronavirus cases rose by more than 400,000 for the first time, a record one-day increase as much of Europe enacts new restrictions to curb the outbreak.

President Donald Trump began a fourth day of treatment for Covid-19 at a military hospital outside Washington, with the severity of his illness unclear barely four weeks before Americans go to the polls to decide whether to reelect him.

The number of novel coronavirus cases in the United States topped 7 million – more than 20% of the world’s total – as Midwest states reported spikes in Covid-19 infections in September, according to a Reuters tally.