BioSpace reviews some of the more interesting scientific studies recently published, including an unusual molecular chaperone implicated in Alzheimer’s disease.

California ordered nearly 40 million people to stay home and New York state on Friday told all non-essential workers to do the same while pleading for more medical personnel and supplies to treat coronavirus cases that could overwhelm hospitals.

In these days of the COVID-19 epidemic, many in the pharma industry are facing the challenge of accessing their customers and engaging in communication. The good news is that there are virtual solutions and approaches that are proven to deliver when in-person selling is limited or no longer an option.

As the world experiences a global pandemic of SARS-CoV-2 – the novel coronavirus that causes COVID-19 – it may be instructional to look at the last major pandemic, the H1N1 influenza pandemic of 2009.

The FDA Guidance on Conduct of Clinical Trials of Medical Products During COVID-19 Pandemic are “a really good first step in ensuring that clinical trials continue with minimum disruption,” according to Jim Kremidas, executive director of the Association of Clinical Research Professionals (ACRP).

A quantitative survey conducted by Continuum Clinical shows clinical research study sites are rapidly becoming more concerned about COVID-19-related interruptions to clinical trial recruitment and retention, with U.S. site concern jumping from 25 percent to 47 percent – an 88 percent increase over just 4 days.

Johnson & Johnson announced that, although there have been anecdotal and unsubstantiated reports that darunavir – marketed by the company’s Janssen business unit as Prezista – is being used in treatment, there is no evidence that the HIV medicine has any effect against SARS-CoV-2.

As the world shifts toward a concept of social distancing as part of an attempt to protect against the novel coronavirus, new research is showing the virus that causes COVID-19 is quite stable on hard surfaces, and even in the air.

Researchers with Scripps Research and other institutions around the globe published a study in the journal Nature Medicine debunking the theory that the novel coronavirus that causes COVID-19 is manmade after an analysis of the genome sequence of SARS-CoV-2.

Hundreds of millions of people worldwide were adjusting to once-in-a-generation measures to battle the coronavirus crisis that is not only killing the old and vulnerable but also threatening prolonged economic misery.