The U.S. flu outbreak worsened over the past week as more people headed to doctors’ offices and emergency rooms, with hospitalizations at the highest in nearly 10 years, U.S. health officials said.

Specialty pharmaceutical company Mallinckrodt plc struck a deal to acquire privately held InfaCare, a Pennsylvania-based company focused on therapies for neonatal and pediatric patients.

Drug developer Otonomy Inc said the U.S. Food and Drug Administration approved its treatment for an inflammatory ear disease. The company said the antibacterial drug, Otiprio, was being tested to treat pediatric patients, with a type of middle ear infection, who were also undergoing a surgery. The pediatric patients were undergoing tympanostomy tube placement surgery, […]

Gene sequencing of more than 1,000 children and adolescents diagnosed with cancer found that as many as 8.5 percent were born with genes that increase their risk of developing cancer, U.S. researchers said on Wednesday. Of the children with cancer risk genes, only 40 percent came from families with a known history of cancer, suggesting […]

Boston-based Third Rock Ventures announced today it had raised $52 million to launch a company called Decibel Therapeutics to work on hearing loss.   Decibel Therapeutics will be headquartered at 215 First Street in Cambridge, Mass. near Kendall Square. The company has already started to hire, planning on having 50 to 60 scientists working by […]

The U.S. Food and Drug Administration said it has approved the use of the painkiller OxyContin in children as young as 11, for severe pain that can’t be adequately treated with other medications. An FDA spokesman said the agency granted the approval Thursday, after the drug’s manufacturer, Purdue Pharma LP, submitted clinical-trial data on the […]