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The Pulse of the Pharmaceutical Industry

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Migraine drugs may repeat RA success

Four pharma heavyweights – including Amgen Inc. – and smaller drug developer Alder Biopharmaceuticals Inc. are racing to bring their migraine biologics to market.

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China Takes Lead in CRISPR Race

China has taken the lead in CRISPR research as an oncology team in that country became the first to inject cells that contained edited genes using the technology.

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Regular nut nibbling linked to low inflammation

Eating a handful of nuts five times per week may reduce inflammation, a condition that contributes to heart disease, diabetes and many other chronic illnesses, say the authors of a recent U.S. study.

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AstraZeneca invests more on mRNA drugs

AstraZeneca has invested another $140 million in Moderna Therapeutics’ drugs based on a molecule known as messenger RNA.

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After the genome, AstraZeneca taps ‘secretome’ for novel drugs

AstraZeneca is diving into the world of proteins secreted by cells – collectively known as the secretome – in the hunt for new drugs and better “cell factories” for making biotech medicines.   The so-called secretome accounts for around one third of human proteins and the idea of mapping them all follows the decoding of […]

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FDA approves Baxalta’s treatment for common bleeding disorder

The U.S. Food and Drug Administration on Tuesday approved Baxalta Inc’s Vonvendi, making it the first engineered protein-based treatment for the world’s most common inherited bleeding disorder. Vonvendi treats Willebrand disease, which is caused by the deficiency or defect in von Willebrand factor, a protein that is critical for blood clotting. The disease affects about […]

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Walnuts each day keep the doctor away?

(Reuters Health) – Eating a handful of walnuts each day might help keep the doctor away, at least for some people who are at risk of developing diabetes, a U.S. study suggests. When people in the study added 56 grams of walnuts (2 ounces, or about 14 walnuts) to their daily diet for six months, […]

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FDA approves expanded use of Bristol-Myers’ skin cancer drug

Bristol-Myers Squibb Co said the U.S. Food and Drug Administration had approved the expanded use of its cancer drug, Opdivo, to treat an additional form of advanced skin cancer. Opdivo, first approved in December 2014, raked in worldwide revenue of $467 million in the nine months ended Sept. 30. The drug has been approved for […]

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AstraZeneca lupus drug impresses in mid-stage trial

AstraZeneca’s experimental lupus drug anifrolumab significantly cut disease activity in a mid-stage clinical trial, boosting hopes for a medicine the company believes could become a $1 billion-a-year seller. The drugmaker said on Tuesday that the new treatment was more effective than another drug, sifalimumab, that it had also been testing in lupus. It has therefore […]

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New device could save millions from septic shock

Prostate cancer, breast cancer and AIDS are all potentially lethal diseases that affect hundreds of thousands each year. But Sepsis, a deadly immune response triggered by infection, kills more people than all of them combined.  According to the National Institutes of Health, more than a million people suffer from sepsis each year in the United […]

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