Insys Therapeutics Inc.’s legal woes deepened as New York’s attorney general filed a lawsuit seeking at least $75 million from the company.

Endo International Plc forecast earnings for the third quarter well above analysts’ estimates amid a lawsuit filed by it against U.S. health regulators that seeks to protect the drugmaker’s blood pressure drug franchise.

As U.S. President Donald Trump declared the opioid crisis a public health emergency, Europe should heed the threat from opioids responsible for America’s deadliest drug epidemic in decades as both regions have seen rises in prescription rates of such medicines, which can be a gateway to dangerous derivatives according to experts.