BioNTech and Pfizer’s Covid-19 vaccine candidate is expected to be ready to seek regulatory approval by the end of 2020, the Wall Street Journal reported, citing the German biotech firm’s chief executive officer.

Record-breaking coronavirus cases and deaths in several U.S. states are dimming hopes of economic recovery, with cellphone data showing shoppers are staying away from stores in areas where cases are rising the most.

The United States reported more than 59,000 new COVID-19 cases on Wednesday, the biggest increase ever reported by a country in a single day, according to a Reuters tally.

New Jersey Governor Phil Murphy said he would sign an executive order requiring people to wear face coverings outdoors to prevent a resurgence of the novel coronavirus whenever social distancing is not possible.

The U.S. coronavirus outbreak crossed a grim milestone of over 3 million confirmed cases as more states reported record numbers of new infections, and Florida faced an impending shortage of intensive care unit hospital beds.

The United States saw a 27 percent increase in new cases of COVID-19 in the week ended July 5 compared to the previous seven days, with 24 states reporting positivity test rates above the level that the World Health Organization flagged as concerning.

Rising coronavirus cases in 39 U.S. states cast a shadow over the nation’s Fourth of July celebrations as health experts worried that holiday parties will cause a further spike in infections that could overwhelm hospitals.

The United States reported more than 55,000 new COVID-19 casesy, a new daily global record for the coronavirus pandemic, as infections rose in a majority of states.

New U.S. COVID-19 cases rose by nearly 50,000 on Wednesday, according to a Reuters tally, marking the biggest one-day spike since the start of the pandemic.

Americans’ anxieties over the spread of the coronavirus are at the highest in more than a month, a Reuters/Ipsos poll showed on Wednesday, as California recorded the state’s largest single-day spike in cases since the pandemic began.