The number of coronavirus deaths in the United States crossed 300,000 on Dec. 14, according to a Reuters tally, as the hardest hit nation rolled out its first vaccine inoculations on the same day.

U.S. coronavirus cases crossed the 15 million mark on Dec. 8 as regulators moved a step closer to approving a Covid-19 vaccine and Britain started inoculating people, offering hope of slowing a pandemic that killed 15,000 Americans in the previous week.

President-elect Joe Biden made his selections for two key public health positions, sources said, as he prepares to take office in January while the coronavirus pandemic rages to new levels across the United States.

The mayor of San Francisco ordered new lockdowns and business restrictions across the Bay Area in the face of the Covid-19 surge, as political leaders nationwide ramp up pressure on Americans to stay home until vaccines can be distributed.

U.S. leaders urgently called on Americans to wear masks and threatened even more drastic stay-at-home orders after deaths from the coronavirus set a single-day record, with two people dying every minute.

The United States set single-day records for new infections and deaths as California’s governor said he would impose some of the nation’s strictest stay-at-home orders in the coming days when intensive care units are expected to reach capacity.

The global tally of confirmed coronavirus cases hit 60 million on Nov. 25, with the pace of new infections accelerating and the United States reporting record numbers of hospitalizations, according to a Reuters tally.

The United States recorded the country’s 12th million Covid-19 case, even as millions of Americans were expected to travel for the upcoming Thanksgiving holiday, ignoring warnings from health officials about furthering the spread of the infectious disease.

The number of people hospitalized with Covid-19 in the United States jumped nearly 50% in a 14-day period, straining the nation’s healthcare system and forcing states to impose new restrictions to curb the alarming spread of the coronavirus.

The number of Covid-19 deaths in the United States crossed 250,000, according to a Reuters tally, as a third coronavirus wave brings a fresh surge in infections and puts immense strain on the healthcare system.