Larger clinical trials are needed to assess whether Roche’s Actemra (tocilizumab) can cut death rates among the sickest Covid-19 patients after a small study found the arthritis drug was no better than standard care in severe cases.
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Oxford scientists are preparing to rapidly produce new versions of their vaccine to combat emerging more contagious Covid-19 variants discovered in the UK, South Africa and Brazil, The Telegraph reported.
The new Covid-19 variant identified in South Africa can evade the antibodies that attack it in treatments using blood plasma from previously recovered patients, and may reduce the efficacy of the current line of vaccines, according to scientists.
Joe Biden is resetting the United States’ response to the Covid-19 crisis after being sworn in as president to lead a country reeling from the nation’s worst public health crisis in more than a century.
The U.S. Food and Drug Administration approved Merck & Co. and Bayer AG’s heart failure drug Verquvo (vericiguat), an orally administered soluble guanylate cyclase stimulator.
An investigational oral MK2 inhibitor from clinical-stage biopharmaceutical company Aclaris Therapeutics was safe and associated with promising reductions in inflammatory markers in a 12-week, Phase II study of patients with moderate to severe rheumatoid arthritis (RA).
Merck KGaA’s drug development program suffered a setback with the company’s most important experimental medicine as the cancer treatment bintrafusp alfa, being jointly developed by GlaxoSmithKline, failed early in a lead trial.
The U.S. Food and Drug Administration accepted for review Impel NeuroPharma’s 5O5(b)(2) New Drug Application (NDA) for INP104 for the acute treatment of migraine headaches with or without aura in adults.
The Covid-19 vaccine developed by Pfizer and BioNTech is likely to protect against a more infectious variant of the virus discovered in Britain which has spread around the world, according to results of further lab tests.
Stephen Byers, Ph.D., associate director and professor of oncology at Georgetown Lombardi, and his team published a paper in the journal Gastroenterology regarding their findings of a novel target for pancreatic cancer therapy.