A major British study into mixing Covid-19 vaccines found that people had a better immune response when they received a first dose of AstraZeneca or Pfizer-BioNTech shots followed by Moderna nine weeks later, according to the results on December 6.
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Survivors of previous infection with the virus that causes SARS-CoV-2 may be at higher risk for re-infection with the Omicron variant than with earlier versions of the virus, preliminary findings show. Additionally, a booster shot of the Pfizer/BioNTech Covid-19 vaccine appears to provide strong protection – at least in the short term – according to data from Israel.
Healthcare disruptions linked to the coronavirus pandemic helped malaria kill 69,000 more people in 2020 than the previous year, but a worst-case scenario was averted, the World Health Organization said on December 6.
Shares of Reata Pharmaceuticals were down nearly 40 percent the morning of December 6 after briefing documents released by the U.S. Food and Drug Administration revealed an unflattering opinion of the company’s experimental drug for Alport syndrome, bardoxolone.
Members of the Sackler family on December 6 said billions of dollars they collected from Purdue Pharma before the company filed for Chapter 11 was the result of extra cash, not part of a “secret plan” to abuse the bankruptcy system.
Future pandemics could be even more lethal than COVID-19 so the lessons learned from the outbreak must not be squandered and the world should ensure it is prepared for the next viral onslaught, one of the creators of the Oxford-AstraZeneca vaccine said.
Merck announced a pause in enrollment for the IMPOWER 22 (MK-8591-022) and IMPOWER 24 (MK-8591-024) Phase 3 clinical studies evaluating investigational, once-monthly, oral islatravir (ISL) – a nucleoside reverse transcriptase translocation inhibitor – for pre-exposure prophylaxis (PrEP) in people at high risk of HIV-1 infection.
Austin, Texas-based Aeglea Biotherapeutics reported what initially appears to be positive outcomes for the company’s Phase III PEACE trial of pegzilarginase in Arginase 1 Deficiency (ARG1-D), a rare, progressive and debilitating disease marked by high levels of the amino acid arginine.
New York City Mayor Bill de Blasio said on December 6 he planned to issue a COVID-19 vaccine mandate for private-sector employers that will go into effect on Dec. 27, calling it a “pre-emptive strike.”
The latest updates from Mesoblast’s Phase III trial on rexlemestrocel-L show that the drug provides the highest benefit when used in patients with certain types of chronic heart failure.