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4

Researchers develop CRISPR mechanism to edit multiple DNA sites at once

Rice University researchers in Houston used the foundation of CRISPR/Cas9 technology to develop “drive-and-process” arrays, or DAP for short. The name may be simple, but the technology is complex and could be as groundbreaking as its predecessor. DAP is a mechanism that enables the editing of multiple DNA sites – rather than one at a time – to comprehensively reverse polygenic diseases resulting from multiple genetic predispositions.

5

Following patient death, FDA puts Foghorn study on partial hold

The U.S. Food and Drug Administration issued a partial clinical hold for Foghorn Therapeutics’ Phase I clinical study, investigating the safety and efficacy of FHD-286 in patients with relapsed and/or refractory acute myelodysplastic leukemia (AML) and myelodysplastic syndromes (MDS). The hold follows a serious adverse event in which a study participant died after developing possible differentiation syndrome.

8

U.S. CDC says COVID vaccine-related myocarditis much lower for children than teens

The U.S. Centers for Diseases Control and Prevention (CDC) on May 19 said reports of heart inflammation linked to the Pfizer/BioNTech COVID-19 vaccine have been much lower in 5- to 11-year-old boys than in adolescents and young men, representing only a slightly elevated rate than normal.

10

Life sciences companies shore up resources as US confirms first monkeypox case

A man in Massachusetts became the first person reported to have a case of monkeypox in the United States since 2021. The man contracted monkeypox after traveling to Canada, although Quebec’s Ministry of Health and Social Services told CBC News that no cases had been reported to the agency. SIGA Technologies is prepared to provide treatment to those infected with monkeypox.