Tag Archive for: cancer vaccine

Moderna shares rose 8% in morning trade on Tuesday after the company’s individualized cancer vaccine developed with Merck showed positive response in an early-stage trial in patients with a type of head and neck cancer.

Nearly a third of patients with advanced liver cancer who received a personalized vaccine developed by Geneos Therapeutics along with an immunotherapy drug in a small, early trial saw their tumors shrink, U.S. researchers reported on Sunday.

According to Bavarian Nordic, its cancer vaccine TAEK-VAC has reached a stage where more investments are required. The company would also have faced stiff competition in the cancer vaccine space.

Moderna said the companies would use Immatics’ drug discovery platform to develop mRNA-based cancer vaccines, and also study its own cancer vaccine for use in combination with Immatics’ cancer therapy IMA203.

Moderna and China’s CARsgen Therapeutics are collaborating to combine their respective mRNA therapeutic cancer vaccine with a solid tumor CAR T cell therapy, the Chinese biotech announced on Monday.

Adding an experimental mRNA-based vaccine from Moderna and Merck reduced the risk that the most deadly skin cancer would spread by 65% over treatment with an immunotherapy alone in a midstage trial, the companies reported today.

In addition to becoming a Nasdaq-listed company, the focus of Elicio moving forward will be a therapeutic cancer vaccine candidate that targets mKRAS-driven tumors.

A combination of Moderna’s melanoma vaccine and Merck’s immunotherapy Keytruda cut the risk of skin cancer’s recurrence or death by 44% compared with Keytruda alone in a mid-stage trial.