Data from an early-stage study showed that Eli Lilly’s investigational RNA silencing therapeutic lepodisiran can induce sharp and durable reductions in serum lipoprotein(a) levels, the company revealed in a read-out presented over the weekend at the 2023 Scientific Sessions of the American Heart Association.
Tag Archive for: cholesterol
When given at potentially therapeutic doses, Verve’s base editor led to strong reductions in LDL cholesterol and PCSK9 levels in patients with heterozygous familial hypercholesterolemia.
For Daiichi Sankyo, results from the Phase III CLEAR trial of Esperion Therapeutics’ cholesterol-lowering candidate Nexletol (bempedoic acid) were not convincing enough to trigger a milestone payment, Esperion announced in an SEC filing posted Wednesday.