J&J, AbbVie, Genmab and Genentech are presenting new data at next month’s American Society of Hematology meeting on the therapeutic potential of their therapies in multiple myeloma and mantle cell lymphoma.
The biotech company has bought the global rights to an investigational oral CDK2 inhibitor from Ensem Therapeutics in a licensing agreement valued at up to $1.33 billion if all milestones are met.
The U.S. health regulator will not meet its Dec. 16 deadline on the use of Bristol Myers Squibb and partner 2seventy bio’s blood cancer therapy in earlier lines of treatment as it plans to seek the advice of independent experts before making a decision, the companies said.
The company won the third FDA approval in a month for the anti-PD-1 blockbuster, allowing its first-line use in locally advanced unresectable or metastatic gastric or gastroesophageal junction adenocarcinoma.
The drugs, Folotyn and Beleodaq, have already been on the market for nearly a decade or more. They were approved under the U.S. Food and Drug Administration’s accelerated pathway in 2009 and 2014, respectively, for treating a rare form of blood cancer.
A pair of new initiatives are infusing money into life sciences innovation in New York at a time when biotech funding is generally scarce. Together, the recently-announced projects, spearheaded by the state and the Chan Zuckerberg Initiative, will bring about $370 million in funding to biotech in the Empire State.
The drug, to be sold under the brand name Augtyro, is set to compete in a crowded market for lung cancer treatments that includes Bristol Myers’ other cancer treatment Opdivo and rival cancer drugs from Roche, Merck, and AstraZeneca.
When given concurrently with chemoradiotherapy, AstraZeneca’s Imfinzi in a late-stage lung cancer study did not lead to significant improvements in progression-free survival versus chemoradiotherapy alone.
The company said that the marketing authorization decision could come early next year.
The campaign, “You Can Focus on the Things You’re Loving,” empowers patients by arming them with the information they need to understand the treatment options for chronic lymphocytic leukemia so they can focus on the activities that they enjoy.