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The agency will require new safety warnings to be added in the prescribing information on labels for opioid pain relievers, including a warning about increased sensitivity to pain.

A federal appeals court on Friday overturned the conviction of a doctor accused of unlawfully prescribing addictive opioids in Arizona and Wyoming after the U.S. Supreme Court issued a ruling in his favor that made it harder to prosecute such cases.

The company in November finalized the settlement agreement to resolve thousands of U.S. lawsuits over the marketing of opioid painkillers and agreed to pay up to $4.25 billion, including a supply of the overdose drug naloxone.

Under the deals, first announced in July, Israel-based Teva will pay up to $4.25 billion, including a supply of the overdose drug naloxone. AbbVie will pay up to $2.37 billion. The final amounts of the settlements will depend on how many state and local governments opt into them.

Teva Pharmaceuticals will pay up to $4.2 billion in the United States to settle claims related to its role in fueling the country’s opioid crisis, New York Attorney General Letitia James said on Thursday.

Researchers chasing long COVID cures are eager to learn whether naltrexone, a generic drug typically used to treat alcohol and opioid addiction, can offer benefits to millions suffering from pain, fatigue and brain fog months after a coronavirus infection.

The U.S. Supreme Court on Monday gave two doctors found guilty of misusing their licenses in the midst of the U.S. opioid epidemic to write thousands of prescriptions for addictive pain medications another chance to challenge their convictions.

Walmart Inc. and CVS Health Corp. said on Wednesday they would stop filling prescriptions for controlled substances issued by telehealth startups Cerebral Inc. and Done Health.

Teva Pharmaceutical Industries and AbbVie’s Allergan unit reached a settlement worth $161.5 million to resolve claims the companies fueled an opioid epidemic in West Virginia, state attorney general Patrick Morrisey said on Wednesday.