Tag Archive for: paroxysmal nocturnal hemoglobinuria (PNH)

The U.S. Food and Drug Administration has approved Apellis Pharmaceuticals Inc.’s drug to treat an advanced eye disorder that is one of the leading causes of blindness globally, the company said on Friday.

Data from the Phase III COMMODORE 2 study show Roche-subsidiary Genentech’s investigational antibody crovalimab is non-inferior to AstraZeneca’s Soliris (eculizumab), the current standard of care in paroxysmal nocturnal hemoglobinuria (PNH).

Novartis reported Thursday that a Phase III trial of iptacopan met its primary endpoint in paroxysmal nocturnal hemoglobinuria (PNH) – the company’s second win in this indication in as many months.

New Phase III data shows Novartis’ experimental iptacopan demonstrated superiority against AstraZeneca subsidiary Alexion’s Soliris and Ultomiris in paroxysmal nocturnal hemoglobinuria (PNH).