Tag Archive for: primary endpoint

Otsuka Pharmaceuticals on Monday announced that its investigational drug candidate AVP-786 fell short of its primary efficacy endpoint in a Phase III trial evaluating its effects as a treatment for agitation in Alzheimer’s disease.

The first-in-class antibody-drug conjugate—in combination with Merck’s Keytruda—has shown promising results in a Phase II study of patients with metastatic non-small cell lung cancer.

Merck released Phase IIb data showing that its hypercholesterolemia hopeful, MK-0616, met the primary endpoint of significantly decreasing low-density lipoprotein cholesterol.

Novartis’ positive-third quarter growth report Tuesday was marred slightly by several clinical setbacks that resulted in the termination of studies in liver transplant and non-small cell lung cancer. 

Bristol Myers Squibb (BMS) announced late-breaking data Wednesday showing that deucravacitinib, an allosteric tyrosine kinase 2 inhibitor, met the primary endpoint in the treatment of systemic lupus erythematosus.

RhoVac AB announced Tuesday that the company’s prostate cancer drug candidate failed to meet targets in a Phase IIb study.