Researchers at Hokkaido University in Japan, in a collaboration with American scientists, may have identified neural crosstalk as the mechanism that drives widespread inflammation in inflammatory diseases, such as rheumatoid arthritis (RA), psoriasis and atherosclerosis.
Covid-19 Wins and Losses: Genentech’s Actemra Flunks Trial; Vir & GSK’s Antibody Dazzles
Clinical Trials, COVID-19 Antibodies, Covid-19 Data, Covid-19 Pneumonia, Genentech, Gilead, GlaxoSmithKline, Hospitalized COVID-19 Patients, Independent Data Monitoring Committee (IDMC), Primary Endpoints, R&D, Remdesivir, Rheumatoid Arthritis, Vir BiotechnologyGenentech reported that the company’s rheumatoid arthritis drug Actemra failed to hit the primary endpoint in a Covid-19 trial, while Vir and GlaxoSmithKline’s antibody against Covid-19 demonstrated 85 percent efficacy.
Gilead Sciences Inc. decided not to pursue the U.S. Food and Drug Administration’s approval of the company’s experimental rheumatoid arthritis treatment, filgotinib, following a meeting with the health regulator.
Kymera Therapeutics entered a strategic collaboration deal with Sanofi focused on developing and commercializing protein degrader therapies that target IRAK4 in immune-inflammatory diseases, such as rheumatoid arthritis.