New cases of Covid-19 rose in 27 out of 50 U.S. states in September compared with August, led by an increase of 111% in Wisconsin, according to a Reuters analysis.

The number of tests coming back positive for Covid-19 is topping 25% in several states in the U.S. Midwest as cases and hospitalizations also surge in the region, according to a Reuters analysis.

Better-than-expected social distancing practices have led an influential research model to lower the projected U.S. coronavirus death toll by 12 percent, while predicting some states may be able to safely begin easing restrictions as early as May 4.