New U.S. COVID-19 cases rose by nearly 50,000 on Wednesday, according to a Reuters tally, marking the biggest one-day spike since the start of the pandemic.

Florida and four other states recorded daily highs for cases of COVID-19 on Saturday, highlighting the worsening spread of the coronavirus in parts of the U.S. South and West, prompting some officials to roll back their reopening plans.

The United States recorded 45,242 new cases of COVID-19 on Friday – the largest single-day increase of the pandemic – according to a Reuters tally, bringing the total number of Americans who have tested positive to at least 2.48 million.

Government experts believe more than 20 million Americans could have contracted the coronavirus – 10 times more than official counts – indicating many people without symptoms have or have had the disease, senior administration officials said.

Havas Health & You (HH&Y) announced the launch of Havas Mango, a Miami-based collective aiming to reimagine wellness and build experiences that help people live their best lives.

The U.S. death toll from the novel coronavirus rose to more than 40,000 on Sunday, the highest in the world and almost double the number of deaths in the next highest country Italy, according to a Reuters tally.

Litigation against OxyContin maker Purdue Pharma LP intensified as six more U.S. states announced lawsuits.